C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein phosphatase 1B, magnesium dependent, beta isoform
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000080217 Ppm1b-201 ENSMUSG00000061130 10090 + 17:84958001-85014776 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000080217
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000080217 4.174±0.52 4.711±0.00 8.860±0.82 13.867±6.03 2.607±0.49 3.464±0.84 7.339±1.15 3.416±0.69 9.295±3.73 5.023±1.67 16.819±1.40 5.805±1.95 6.892±2.20

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001XM CIL_0001XM_0002 CGP 17:84705247-85023991
CIL_0004BC CIL_0004BC_0002 CGP 17:84956741-85064243

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0004722 IEA protein serine/threonine phosphatase activity
GO:0005515 IEA protein binding
GO:0030145 IEA manganese ion binding
GO:0032688 IEA negative regulation of interferon-beta production
GO:0035970 IEA peptidyl-threonine dephosphorylation
GO:0042347 IEA negative regulation of NF-kappaB import into nucleus
GO:0043124 IEA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0050687 IEA negative regulation of defense response to virus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000013103 ppm1ba-201 protein_coding Danio_rerio 0 556
ENSDART00000144755 ppm1ba-001 protein_coding Danio_rerio 0 556
ENSDART00000126725 ppm1ba-002 protein_coding Danio_rerio 0 353
ENST00000282412 PPM1B-001 protein_coding Homo_sapiens 0 2582
ENST00000345249 PPM1B-003 protein_coding Homo_sapiens 0 1192
ENST00000378540 PPM1B-007 processed_transcript Homo_sapiens 0 1794
ENST00000378551 PPM1B-002 protein_coding Homo_sapiens 0 1796
ENST00000409432 PPM1B-004 protein_coding Homo_sapiens 0 1794
ENST00000409473 PPM1B-011 protein_coding Homo_sapiens 0 867
ENST00000409486 PPM1B-006 retained_intron Homo_sapiens 0 1574
ENST00000419807 PPM1B-005 protein_coding Homo_sapiens 0 1712
ENST00000459690 PPM1B-010 processed_transcript Homo_sapiens 0 228
ENST00000487286 PPM1B-009 processed_transcript Homo_sapiens 0 228
ENST00000488866 PPM1B-012 retained_intron Homo_sapiens 0 226

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