C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: piccolo (presynaptic cytomatrix protein)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000061601 Pclo 10090 + 5:14514918-14860184 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030691 Pclo-001 14514918-14859115 protein_coding
  ENSMUST00000182407 Pclo-002 14514918-14795993 protein_coding
  ENSMUST00000182426 Pclo-003 14514993-14860184 retained_intron
  ENSMUST00000182915 Pclo-004 14680863-14796004 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030691ENSMUST00000182407ENSMUST00000182426ENSMUST00000182915
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030691 N/A 0.161±0.05 N/A N/A N/A 0.054±0.00 N/A N/A 0.016±0.00 N/A 0.010±0.01 N/A N/A N/A
ENSMUST00000182407 N/A 0.113±0.04 N/A 2.057±0.93 0.057±0.00 0.035±0.03 0.020±0.00 0.116±0.00 0.010±0.01 N/A 0.016±0.00 0.099±0.03 0.009±0.00 0.094±0.00
ENSMUST00000182426 0.032±0.00 N/A 0.038±0.00 1.658±0.00 0.036±0.02 0.033±0.00 0.024±0.00 0.121±0.03 N/A 0.071±0.03 0.006±0.00 0.062±0.01 0.009±0.00 0.035±0.01
ENSMUST00000182915 0.114±0.04 0.323±0.11 0.465±0.06 6.305±3.96 0.081±0.01 0.044±0.02 0.036±0.02 0.580±0.03 0.016±0.01 0.140±0.06 0.018±0.01 0.243±0.08 0.013±0.01 0.054±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003CW CIL_0003CW_0002 CGP 5:14025276-14860184

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005509 ISS calcium ion binding
GO:0005515 IPI protein binding
GO:0005522 IDA profilin binding
GO:0005544 ISS calcium-dependent phospholipid binding
GO:0007010 IDA cytoskeleton organization
GO:0014069 IDA postsynaptic density
GO:0016080 NAS synaptic vesicle targeting
GO:0017157 IDA regulation of exocytosis
GO:0019933 IDA cAMP-mediated signaling
GO:0030054 IEA cell junction
GO:0030073 IDA insulin secretion
GO:0045202 IDA synapse

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000012482 pclob piccolo (presynaptic cytomatrix protein) b protein_coding Danio_rerio
ENSDARG00000063299 pcloa piccolo (presynaptic cytomatrix protein) a protein_coding Danio_rerio
ENSG00000186472 PCLO piccolo presynaptic cytomatrix protein protein_coding Homo_sapiens

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