C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutamate receptor, metabotropic 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000063239 Grm4 10090 - 17:27422387-27513341 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000118161 Grm4-002 27425904-27513341 protein_coding
  ENSMUST00000118489 Grm4-001 27422387-27503304 protein_coding
  ENSMUST00000146277 Grm4-003 27450156-27473316 retained_intron
  ENSMUST00000147865 Grm4-004 27451629-27473067 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000118161ENSMUST00000118489ENSMUST00000146277ENSMUST00000147865
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000118161 0.039±0.00 0.038±0.02 0.041±0.00 5.703±2.98 0.045±0.02 0.059±0.04 0.107±0.05 0.011±0.00 0.005±0.00 0.147±0.03 0.015±0.00 0.819±0.53 0.025±0.03 0.101±0.04
ENSMUST00000118489 0.008±0.00 0.042±0.02 N/A N/A N/A 0.023±0.00 N/A 0.013±0.01 0.007±0.00 0.076±0.00 N/A N/A 0.022±0.01 0.066±0.00
ENSMUST00000146277 0.048±0.00 N/A N/A N/A N/A N/A 0.115±0.00 N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000147865 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.196±0.08 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000251 CIL_000251_0002 CGP 17:27422387-27563674

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 IEA activation of MAPK activity
GO:0001642 IBA group III metabotropic glutamate receptor activity
GO:0004930 ISS G-protein coupled receptor activity
GO:0005516 IEA calmodulin binding
GO:0005622 IEA intracellular
GO:0005887 IBA integral component of plasma membrane
GO:0007196 IBA adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
GO:0007268 IMP synaptic transmission
GO:0007612 IMP learning
GO:0008066 IEA glutamate receptor activity
GO:0031410 IEA cytoplasmic vesicle
GO:0042734 IBA presynaptic membrane
GO:0043005 IDA neuron projection
GO:0043195 IEA terminal bouton
GO:0043198 IEA dendritic shaft
GO:0043410 IEA positive regulation of MAPK cascade
GO:0048306 IEA calcium-dependent protein binding
GO:0048787 IEA presynaptic active zone membrane
GO:0051966 IBA regulation of synaptic transmission, glutamatergic

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040156 grm4 glutamate receptor, metabotropic 4 protein_coding Danio_rerio
ENSG00000124493 GRM4 glutamate receptor, metabotropic 4 protein_coding Homo_sapiens

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