C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: glutamate receptor, metabotropic 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000118161 Grm4-002 ENSMUSG00000063239 10090 - 17:27425904-27513341 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000118161
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000118161 0.039±0.00 0.038±0.02 0.041±0.00 5.703±2.98 0.045±0.02 0.059±0.04 0.107±0.05 0.011±0.00 0.005±0.00 0.147±0.03 0.015±0.00 0.819±0.53 0.025±0.03 0.101±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000251 CIL_000251_0002 CGP 17:27422387-27563674

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 IEA activation of MAPK activity
GO:0001642 IBA group III metabotropic glutamate receptor activity
GO:0005516 IEA calmodulin binding
GO:0005622 IEA intracellular
GO:0005887 IBA integral component of plasma membrane
GO:0007196 IBA adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway
GO:0007268 IMP synaptic transmission
GO:0007612 IMP learning
GO:0008066 IEA glutamate receptor activity
GO:0031410 IEA cytoplasmic vesicle
GO:0042734 IBA presynaptic membrane
GO:0043195 IEA terminal bouton
GO:0043198 IEA dendritic shaft
GO:0043410 IEA positive regulation of MAPK cascade
GO:0048306 IEA calcium-dependent protein binding
GO:0048787 IEA presynaptic active zone membrane
GO:0051966 IBA regulation of synaptic transmission, glutamatergic

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000058736 grm4-201 protein_coding Danio_rerio 0 1354
ENSDART00000013311 grm6a-201 protein_coding Danio_rerio 0 965
ENSDART00000138993 grm6a-001 protein_coding Danio_rerio 0 963
ENSDART00000109044 grm8a-201 protein_coding Danio_rerio 0 828
ENST00000231188 GRM6-201 protein_coding Homo_sapiens 0 1092
ENST00000374177 GRM4-002 protein_coding Homo_sapiens 0 2246
ENST00000374181 GRM4-201 protein_coding Homo_sapiens 0 2246
ENST00000455714 GRM4-005 protein_coding Homo_sapiens 0 3027
ENST00000517717 GRM6-001 protein_coding Homo_sapiens 0 1092
ENST00000519003 GRM6-004 retained_intron Homo_sapiens 0 350
ENST00000535756 GRM4-202 protein_coding Homo_sapiens 0 3024
ENST00000538487 GRM4-001 protein_coding Homo_sapiens 0 3755
ENST00000544773 GRM4-003 protein_coding Homo_sapiens 0 3029
ENST00000545715 GRM4-009 processed_transcript Homo_sapiens 0 2556
ENST00000607916 GRM4-006 retained_intron Homo_sapiens 0 774
ENST00000609222 GRM4-004 protein_coding Homo_sapiens 0 3024
ENST00000609278 GRM4-010 nonsense_mediated_decay Homo_sapiens 0 2638
ENST00000609860 GRM4-008 retained_intron Homo_sapiens 0 2741
ENST00000609973 GRM4-007 retained_intron Homo_sapiens 0 496

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