C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nuclear receptor subfamily 6, group A, member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000063972 Nr6a1 10090 - 2:38723370-38927688 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000076275 Nr6a1-201 38723374-38926217 protein_coding
  ENSMUST00000112877 Nr6a1-001 38723370-38927688 protein_coding
  ENSMUST00000123099 Nr6a1-005 38781920-38784469 processed_transcript
  ENSMUST00000123342 Nr6a1-008 38737597-38740464 processed_transcript
  ENSMUST00000128688 Nr6a1-007 38738727-38742957 processed_transcript
  ENSMUST00000132636 Nr6a1-004 38740424-38785111 processed_transcript
  ENSMUST00000142113 Nr6a1-003 38739135-38784520 protein_coding
  ENSMUST00000142130 Nr6a1-002 38740543-38926275 protein_coding
  ENSMUST00000156301 Nr6a1-006 38742441-38784469 processed_transcript
  ENSMUST00000168098 Nr6a1-202 38723374-38784515 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000076275ENSMUST00000112877ENSMUST00000128688ENSMUST00000142130ENSMUST00000168098
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000076275 0.445±0.28 0.736±0.22 0.365±0.14 1.096±0.27 0.396±0.17 1.110±0.00 0.262±0.04 0.240±0.05 0.292±0.17 N/A 0.303±0.09 0.919±0.08 3.903±1.83 12.385±7.83
ENSMUST00000112877 0.829±0.41 0.864±0.60 0.602±0.01 0.658±0.28 0.511±0.29 0.955±0.50 0.138±0.02 0.682±0.19 0.563±0.41 0.858±0.18 0.154±0.00 2.112±0.95 1.852±0.37 23.102±10.08
ENSMUST00000128688 N/A 1.470±0.00 N/A N/A 1.457±0.53 N/A 0.454±0.00 N/A N/A N/A N/A 2.423±0.03 N/A 60.870±3.88
ENSMUST00000142130 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 60.115±0.00
ENSMUST00000168098 N/A 0.942±0.35 N/A N/A 0.183±0.00 0.891±0.00 N/A 0.805±0.00 0.669±0.50 N/A 0.522±0.13 1.364±0.17 1.085±0.05 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008N3 CIL_0008N3_0002 VISTA 2:38235055-38837083
CIL_00098L CIL_00098L_0002 VISTA 2:38294702-38895720
CIL_00075I CIL_00075I_0002 CGP 2:38692656-38927688
CIL_00075J CIL_00075J_0002 CGP 2:38723370-38963753

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000978 IMP RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IDA DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005667 IDA transcription factor complex
GO:0006351 IEA transcription, DNA-templated
GO:0007275 IEA multicellular organismal development
GO:0007276 IEP gamete generation
GO:0007283 IEA spermatogenesis
GO:0008270 IEA zinc ion binding
GO:0030154 IEA cell differentiation
GO:0042803 IDA protein homodimerization activity
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043565 IDA sequence-specific DNA binding
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018030 nr6a1a nuclear receptor subfamily 6, group A, member 1a protein_coding Danio_rerio
ENSG00000148200 NR6A1 nuclear receptor subfamily 6, group A, member 1 protein_coding Homo_sapiens

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