C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: vaccinia related kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000064090 Vrk2 10090 - 11:26471322-26593999 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000078362 Vrk2-201 26471404-26593920 protein_coding
  ENSMUST00000109504 Vrk2-001 26471322-26591729 protein_coding
  ENSMUST00000124294 Vrk2-003 26533841-26593622 retained_intron
  ENSMUST00000125545 Vrk2-005 26583296-26593603 processed_transcript
  ENSMUST00000133487 Vrk2-006 26534257-26549365 processed_transcript
  ENSMUST00000155728 Vrk2-002 26545395-26593923 retained_intron
  ENSMUST00000156264 Vrk2-004 26547848-26593999 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000078362ENSMUST00000109504ENSMUST00000155728ENSMUST00000156264
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000078362 1.449±0.47 2.941±0.08 N/A 1.176±0.44 N/A 1.086±0.26 1.181±0.39 3.132±2.64 0.823±0.08 0.906±0.54 1.423±1.27 2.971±0.31 2.911±0.86
ENSMUST00000109504 1.053±0.00 3.095±0.47 1.100±0.48 2.198±0.00 1.338±0.18 N/A 0.971±0.38 3.202±2.69 1.234±0.36 1.337±0.52 2.394±2.30 3.912±1.64 3.284±0.92
ENSMUST00000155728 N/A N/A N/A 0.401±0.02 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000156264 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.257±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007LM CIL_0007LM_0002 UCNEbase 11:24062983-26981636
CIL_0007WS CIL_0007WS_0002 VISTA 11:26189088-26791733
CIL_0004OQ CIL_0004OQ_0002 CGP 11:26386135-26593999

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004674 IDA protein serine/threonine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005789 ISS endoplasmic reticulum membrane
GO:0006468 IDA protein phosphorylation
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0031966 ISS mitochondrial membrane
GO:0034599 ISS cellular response to oxidative stress
GO:0043408 ISS regulation of MAPK cascade
GO:0046777 IDA protein autophosphorylation
GO:2000659 ISS regulation of interleukin-1-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021547 vrk2 vaccinia related kinase 2 protein_coding Danio_rerio
ENSG00000028116 VRK2 vaccinia related kinase 2 protein_coding Homo_sapiens

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