C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: vaccinia related kinase 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000078362 Vrk2-201 ENSMUSG00000064090 10090 - 11:26471404-26593920 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBreastHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000078362
Transcript ID Adipose Bladder Breast Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000078362 1.449±0.47 2.941±0.08 1.176±0.44 1.086±0.26 1.181±0.39 3.132±2.64 0.823±0.08 0.906±0.54 1.423±1.27 2.971±0.31 2.911±0.86

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007LM CIL_0007LM_0002 UCNEbase 11:24062983-26981636
CIL_0007WS CIL_0007WS_0002 VISTA 11:26189088-26791733
CIL_0004OQ CIL_0004OQ_0002 CGP 11:26386135-26593999

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004674 IDA protein serine/threonine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005789 ISS endoplasmic reticulum membrane
GO:0006468 IDA protein phosphorylation
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0031966 ISS mitochondrial membrane
GO:0034599 ISS cellular response to oxidative stress
GO:0043408 ISS regulation of MAPK cascade
GO:0046777 IDA protein autophosphorylation
GO:2000659 ISS regulation of interleukin-1-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000340157 VRK2-001 protein_coding Homo_sapiens 0 1081
ENST00000412104 VRK2-201 protein_coding Homo_sapiens 0 784
ENST00000417641 VRK2-004 protein_coding Homo_sapiens 0 1079
ENST00000432057 VRK2-002 nonsense_mediated_decay Homo_sapiens 0 942
ENST00000435505 VRK2-005 protein_coding Homo_sapiens 0 1079
ENST00000440705 VRK2-008 protein_coding Homo_sapiens 0 1044

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