C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: vaccinia related kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000028116 VRK2 9606 + 2:57907651-58159920 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000340157 VRK2-001 58046691-58159871 protein_coding
  ENST00000412104 VRK2-201 58046642-58159920 protein_coding
  ENST00000417641 VRK2-004 57907651-58159871 protein_coding
  ENST00000428021 VRK2-003 58046875-58084927 protein_coding
  ENST00000432057 VRK2-002 58046712-58159784 nonsense_mediated_decay
  ENST00000435505 VRK2-005 57907651-58159867 protein_coding
  ENST00000440705 VRK2-008 58046715-58159784 protein_coding
  ENST00000463222 VRK2-007 57907656-58033327 processed_transcript
  ENST00000478687 VRK2-006 57907652-58033663 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000340157ENST00000417641ENST00000432057ENST00000440705
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000340157 2.917±0.00 N/A 3.562±0.00 2.028±0.00 3.403±2.42 2.508±0.00 2.809±0.00 N/A 1.861±0.00 7.673±0.00 2.246±0.06 4.781±0.00
ENST00000417641 N/A 1.936±0.00 N/A N/A 0.666±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000432057 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.128±0.00
ENST00000440705 N/A N/A 2.706±0.00 2.269±0.00 N/A 1.515±0.00 N/A 1.135±0.00 1.388±0.00 14.005±0.00 2.998±2.03 5.048±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008BO CIL_0008BO_0001 VISTA 2:57445240-58046040
CIL_0007ZI CIL_0007ZI_0001 VISTA 2:57618972-58220354
CIL_0007LM CIL_0007LM_0001 UCNEbase 2:57740887-60568309
CIL_0007WS CIL_0007WS_0001 VISTA 2:57829929-58432668

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005783 IDA endoplasmic reticulum
GO:0005789 IDA endoplasmic reticulum membrane
GO:0006468 TAS:IEA protein phosphorylation
GO:0008152 IEA metabolic process
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016032 IEA viral process
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0031966 IDA mitochondrial membrane
GO:0034599 IMP cellular response to oxidative stress
GO:0043408 IMP regulation of MAPK cascade
GO:0046777 IDA protein autophosphorylation
GO:2000659 IMP regulation of interleukin-1-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021547 vrk2 vaccinia related kinase 2 protein_coding Danio_rerio
ENSMUSG00000064090 Vrk2 vaccinia related kinase 2 protein_coding Mus_musculus

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