C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: phosphatase and actin regulator 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000084170 Phactr4-201 ENSMUSG00000066043 10090 - 4:132355930-132422446 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000084170
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000084170 2.446±1.39 4.012±2.64 2.839±0.00 2.924±2.47 1.052±0.48 5.123±2.80 2.396±1.63 7.284±3.36 2.984±1.23 3.984±2.30 0.749±0.19 3.506±1.60 4.721±1.74 1.508±0.32

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099N CIL_00099N_0002 VISTA 4:131775516-132379227
CIL_0001RA CIL_0001RA_0002 CGP 4:132331919-132422489

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001755 IMP neural crest cell migration
GO:0001843 IMP neural tube closure
GO:0003779 IDA actin binding
GO:0004864 IEA protein phosphatase inhibitor activity
GO:0005622 IMP intracellular
GO:0005737 IEA cytoplasm
GO:0007266 IMP Rho protein signal transduction
GO:0008157 IDA protein phosphatase 1 binding
GO:0030027 IDA lamellipodium
GO:0030036 IMP actin cytoskeleton organization
GO:0043085 IDA positive regulation of catalytic activity
GO:0043086 IEA negative regulation of catalytic activity
GO:0048484 IMP enteric nervous system development
GO:0051726 IMP regulation of cell cycle
GO:0061386 IMP closure of optic fissure
GO:0071862 IDA protein phosphatase type 1 activator activity
GO:2001045 IMP negative regulation of integrin-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000373836 PHACTR4-004 protein_coding Homo_sapiens 0 1482
ENST00000373839 PHACTR4-001 protein_coding Homo_sapiens 0 1482
ENST00000463428 PHACTR4-003 processed_transcript Homo_sapiens 0 250
ENST00000493669 PHACTR4-002 processed_transcript Homo_sapiens 0 1085

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