C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: synaptic Ras GTPase activating protein 1 homolog (rat)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000067629 Syngap1 10090 + 17:26941452-26970645 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000081285 Syngap1-201 26941452-26970645 protein_coding
  ENSMUST00000177932 Syngap1-202 26941452-26970541 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainColonLiverMuscleOvaryPlacentaTestisENSMUST00000081285ENSMUST00000177932
Transcript ID Adrenal Brain Colon Liver Muscle Ovary Placenta Testis
ENSMUST00000081285 N/A 17.813±1.27 N/A N/A 0.132±0.00 3.359±0.00 N/A 4.795±0.72
ENSMUST00000177932 1.866±0.32 22.597±0.00 0.811±0.00 0.135±0.00 0.118±0.03 3.896±0.75 0.299±0.00 11.309±1.96

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000915 CIL_000915_0002 VISTA 17:26527896-27128643
CIL_0008HF CIL_0008HF_0002 VISTA 17:26563571-27166666
CIL_000253 CIL_000253_0002 CGP 17:26937973-26970645
CIL_000254 CIL_000254_0002 CGP 17:26941452-26976205

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005097 IDA Rab GTPase activator activity
GO:0005515 IPI protein binding
GO:0005737 IBA cytoplasm
GO:0007265 IDA Ras protein signal transduction
GO:0007389 IMP pattern specification process
GO:0008542 IMP visual learning
GO:0016020 IDA membrane
GO:0016358 IMP dendrite development
GO:0017124 IEA SH3 domain binding
GO:0030054 IEA cell junction
GO:0031235 IBA intrinsic component of the cytoplasmic side of the plasma membrane
GO:0032320 IBA positive regulation of Ras GTPase activity
GO:0032851 IDA positive regulation of Rab GTPase activity
GO:0043113 IMP receptor clustering
GO:0043198 IDA dendritic shaft
GO:0043408 IMP regulation of MAPK cascade
GO:0043524 IMP negative regulation of neuron apoptotic process
GO:0045202 IEA synapse
GO:0046580 ISS negative regulation of Ras protein signal transduction
GO:0048167 ISS regulation of synaptic plasticity
GO:0048169 IGI regulation of long-term neuronal synaptic plasticity
GO:0050771 IDA negative regulation of axonogenesis
GO:0050803 IMP regulation of synapse structure and activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063713 SYNGAP1 (1 of 2) synaptic Ras GTPase activating protein 1 protein_coding Danio_rerio
ENSDARG00000069765 SYNGAP1 (2 of 2) synaptic Ras GTPase activating protein 1 protein_coding Danio_rerio
ENSG00000197283 SYNGAP1 synaptic Ras GTPase activating protein 1 protein_coding Homo_sapiens

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