C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: NLR family, pyrin domain containing 1B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000070390 Nlrp1b 10090 - 11:71153102-71230733 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000094046 Nlrp1b-201 71156000-71228467 protein_coding
  ENSMUST00000108514 Nlrp1b-202 71155993-71201298 protein_coding
  ENSMUST00000108515 Nlrp1b-002 71153102-71201456 protein_coding
  ENSMUST00000108516 Nlrp1b-001 71153127-71230733 protein_coding
  ENSMUST00000136493 Nlrp1b-003 71153102-71230733 nonsense_mediated_decay

Mus musculus EnsemblGRCm38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000094046ENSMUST00000108514ENSMUST00000108515ENSMUST00000108516ENSMUST00000136493
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000094046 N/A 0.076±0.04 N/A 0.105±0.02 0.147±0.00 0.026±0.01 0.033±0.01 0.077±0.04 0.126±0.08 0.026±0.00 N/A 0.020±0.00 0.068±0.03
ENSMUST00000108514 0.226±0.00 0.070±0.00 0.006±0.00 0.219±0.09 0.614±0.42 0.048±0.01 0.112±0.05 0.054±0.02 0.237±0.07 0.011±0.00 0.121±0.05 0.036±0.02 0.031±0.02
ENSMUST00000108515 N/A 0.085±0.01 N/A 0.328±0.09 0.404±0.05 N/A 0.087±0.01 0.054±0.03 N/A 0.030±0.00 0.048±0.00 0.013±0.01 0.017±0.00
ENSMUST00000108516 0.209±0.00 0.134±0.03 0.011±0.00 N/A 0.017±0.00 N/A 0.048±0.02 N/A 0.172±0.00 0.031±0.01 0.067±0.03 0.008±0.00 0.084±0.00
ENSMUST00000136493 0.170±0.07 N/A N/A 0.183±0.18 N/A N/A N/A 0.054±0.04 0.092±0.00 0.029±0.01 0.164±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000N1 CIL_0000N1_0002 CGP 11:71153102-71789647

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005524 IEA ATP binding
GO:0030163 IMP protein catabolic process
GO:0032610 IMP interleukin-1 alpha production
GO:0032611 IMP interleukin-1 beta production
GO:0042981 IEA regulation of apoptotic process
GO:0070269 IMP pyroptosis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088074 caspase recruitment domain family, member 8 protein_coding Danio_rerio
ENSDARG00000088236 caspase recruitment domain family, member 8 protein_coding Danio_rerio
ENSDARG00000094305 caspase recruitment domain family, member 8 protein_coding Danio_rerio
ENSDARG00000096064 caspase recruitment domain family, member 8 protein_coding Danio_rerio
ENSDARG00000096067 caspase recruitment domain family, member 8 protein_coding Danio_rerio
ENSG00000091592 NLRP1 NLR family, pyrin domain containing 1 protein_coding Homo_sapiens

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