C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mutated in colorectal cancers
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000071856 Mcc 10090 - 18:44425061-44812182 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000089874 Mcc-201 44425061-44812182 protein_coding
  ENSMUST00000164666 Mcc-202 44425061-44662266 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000089874ENSMUST00000164666
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000089874 1.818±0.00 1.299±0.50 N/A 0.727±0.37 1.209±0.86 3.304±0.52 N/A 1.068±0.00 5.415±0.78 N/A N/A 2.629±0.68 0.153±0.00 0.243±0.00
ENSMUST00000164666 3.513±1.88 N/A 1.540±0.00 1.515±0.36 1.026±0.61 0.623±0.08 3.321±0.71 1.493±0.97 1.505±0.00 4.048±0.26 0.520±0.15 1.591±0.96 0.699±0.35 0.204±0.13

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004UM CIL_0004UM_0002 CGP 18:44380500-44812182

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0010633 IEA negative regulation of epithelial cell migration
GO:0050680 IEA negative regulation of epithelial cell proliferation
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087450 MCC mutated in colorectal cancers protein_coding Danio_rerio
ENSG00000171444 MCC mutated in colorectal cancers protein_coding Homo_sapiens

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