C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: BCL2/adenovirus E1B interacting protein 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000078566 Bnip3 10090 - 7:138890836-138909519 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000106112 Bnip3-001 138890836-138909506 protein_coding
  ENSMUST00000125359 Bnip3-002 138898710-138909479 processed_transcript
  ENSMUST00000130500 Bnip3-004 138894281-138909495 processed_transcript
  ENSMUST00000141223 Bnip3-005 138894610-138898276 processed_transcript
  ENSMUST00000148970 Bnip3-003 138898540-138909519 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000106112ENSMUST00000130500ENSMUST00000148970
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000106112 69.457±40.28 35.579±8.71 23.207±1.73 8.033±3.45 32.071±12.10 3.280±1.04 30.004±2.51 40.542±2.55 54.116±42.03 13.437±1.67 98.687±15.08 16.991±10.00 36.238±29.49 3.515±1.64
ENSMUST00000130500 N/A N/A N/A N/A N/A 2.454±1.64 N/A N/A 26.955±21.04 N/A N/A 7.237±0.00 N/A 0.332±0.00
ENSMUST00000148970 N/A 71.500±10.09 N/A N/A 17.971±2.70 5.831±1.54 N/A N/A N/A 7.347±0.18 N/A 12.025±5.27 N/A 2.926±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000478 CIL_000478_0003 CGP 7:138846079-138909519
CIL_0001LG CIL_0001LG_0002 CGP 7:138890836-139083976

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 ISS response to hypoxia
GO:0005515 IEA protein binding
GO:0005634 ISS nucleus
GO:0005635 ISS nuclear envelope
GO:0005654 ISS nucleoplasm
GO:0005737 ISS cytoplasm
GO:0005739 ISS mitochondrion
GO:0005741 ISS mitochondrial outer membrane
GO:0005783 IBA endoplasmic reticulum
GO:0006915 ISO apoptotic process
GO:0008219 ISS cell death
GO:0008626 IEA granzyme-mediated apoptotic signaling pathway
GO:0010637 IEA negative regulation of mitochondrial fusion
GO:0030425 ISS dendrite
GO:0031307 ISS integral component of mitochondrial outer membrane
GO:0031966 ISS mitochondrial membrane
GO:0035694 ISS mitochondrial protein catabolic process
GO:0042802 IEA identical protein binding
GO:0042803 IDA protein homodimerization activity
GO:0043065 ISS positive regulation of apoptotic process
GO:0043068 IBA positive regulation of programmed cell death
GO:0043243 IEA positive regulation of protein complex disassembly
GO:0043653 IEA mitochondrial fragmentation involved in apoptotic process
GO:0045837 ISS negative regulation of membrane potential
GO:0046902 ISS regulation of mitochondrial membrane permeability
GO:0046982 IEA protein heterodimerization activity
GO:0048102 IEA autophagic cell death
GO:0050873 IDA brown fat cell differentiation
GO:0051020 IEA GTPase binding
GO:0051402 ISS neuron apoptotic process
GO:0051607 ISS defense response to virus
GO:0055093 IEA response to hyperoxia
GO:0070301 IEA cellular response to hydrogen peroxide
GO:0071260 IEA cellular response to mechanical stimulus
GO:0071279 IEA cellular response to cobalt ion
GO:0071456 IEA cellular response to hypoxia
GO:0072593 ISS reactive oxygen species metabolic process
GO:0090141 IEA positive regulation of mitochondrial fission
GO:0090200 IEA positive regulation of release of cytochrome c from mitochondria
GO:0097193 IGI intrinsic apoptotic signaling pathway
GO:0097345 ISS mitochondrial outer membrane permeabilization
GO:1901998 IMP toxin transport
GO:1990144 IEA intrinsic apoptotic signaling pathway in response to hypoxia

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022832 bnip4 BCL2/adenovirus E1B interacting protein 4 protein_coding Danio_rerio
ENSDARG00000045033 bnip3 BCL2/adenovirus E1B interacting protein 3 protein_coding Danio_rerio
ENSG00000176171 BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 protein_coding Homo_sapiens

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