C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: BCL2/adenovirus E1B 19kDa interacting protein 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000176171 BNIP3 9606 - 10:131966455-131981931 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000368636 BNIP3-001 131966455-131981931 protein_coding
  ENST00000540159 BNIP3-002 131968228-131981923 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000368636ENST00000540159
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000368636 7.373±0.00 2.244±0.00 1.854±0.00 22.699±6.27 7.694±5.54 6.596±5.33 15.668±12.57 12.851±0.38 11.472±9.27 2.290±0.19 22.141±17.16 4.369±3.50 8.446±1.67 7.395±3.91
ENST00000540159 N/A 1.343±0.00 1.293±0.00 N/A 0.527±0.00 1.597±1.29 N/A N/A 0.972±0.00 1.197±0.00 N/A 1.102±0.54 8.111±0.00 6.294±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000478 CIL_000478_0002 CGP 10:131900644-131981931
CIL_0001LG CIL_0001LG_0001 CGP 10:131966455-132184809

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 ISS response to hypoxia
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005635 IDA nuclear envelope
GO:0005654 ISS nucleoplasm
GO:0005737 ISS cytoplasm
GO:0005739 IDA mitochondrion
GO:0005740 IEA mitochondrial envelope
GO:0005741 IDA mitochondrial outer membrane
GO:0005783 IBA endoplasmic reticulum
GO:0006915 IPI apoptotic process
GO:0008219 ISS cell death
GO:0008626 IDA granzyme-mediated apoptotic signaling pathway
GO:0010508 TAS positive regulation of autophagy
GO:0010637 IDA negative regulation of mitochondrial fusion
GO:0016021 IEA integral component of membrane
GO:0016032 IEA viral process
GO:0030425 ISS dendrite
GO:0031307 IDA integral component of mitochondrial outer membrane
GO:0031966 IDA mitochondrial membrane
GO:0035694 IMP mitochondrial protein catabolic process
GO:0042802 IPI identical protein binding
GO:0042803 IDA protein homodimerization activity
GO:0043065 IEA:IDA positive regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0043068 IDA positive regulation of programmed cell death
GO:0043243 IDA positive regulation of protein complex disassembly
GO:0043653 IDA mitochondrial fragmentation involved in apoptotic process
GO:0045837 IDA negative regulation of membrane potential
GO:0046902 IDA regulation of mitochondrial membrane permeability
GO:0046982 IDA protein heterodimerization activity
GO:0048102 IEA autophagic cell death
GO:0050873 IEA brown fat cell differentiation
GO:0051020 IPI GTPase binding
GO:0051402 ISS neuron apoptotic process
GO:0051607 IDA defense response to virus
GO:0055093 IEA response to hyperoxia
GO:0070301 IEA cellular response to hydrogen peroxide
GO:0071260 IEP cellular response to mechanical stimulus
GO:0071279 IMP cellular response to cobalt ion
GO:0071456 IMP cellular response to hypoxia
GO:0072593 IDA reactive oxygen species metabolic process
GO:0090141 IDA positive regulation of mitochondrial fission
GO:0090200 IDA positive regulation of release of cytochrome c from mitochondria
GO:0097193 IEA intrinsic apoptotic signaling pathway
GO:0097345 IDA mitochondrial outer membrane permeabilization
GO:1901998 IEA toxin transport
GO:1990144 IMP intrinsic apoptotic signaling pathway in response to hypoxia

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022832 bnip4 BCL2/adenovirus E1B interacting protein 4 protein_coding Danio_rerio
ENSDARG00000045033 bnip3 BCL2/adenovirus E1B interacting protein 3 protein_coding Danio_rerio
ENSMUSG00000078566 Bnip3 BCL2/adenovirus E1B interacting protein 3 protein_coding Mus_musculus

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