C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Rho guanine nucleotide exchange factor (GEF) 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000047664 Arhgef4-001 ENSMUSG00000037509 10090 + 1:34801704-34813309 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainENSMUST00000047664
Transcript ID Brain
ENSMUST00000047664 54.071±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001J9 CIL_0001J9_0002 CGP 1:34579727-34813309
CIL_0001J8 CIL_0001J8_0002 CGP 1:34678188-34843065

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005085 ISS guanyl-nucleotide exchange factor activity
GO:0005737 IEA cytoplasm
GO:0019904 IEA protein domain specific binding
GO:0030032 ISS lamellipodium assembly
GO:0030676 ISS Rac guanyl-nucleotide exchange factor activity
GO:0032855 ISS positive regulation of Rac GTPase activity
GO:0035556 IEA intracellular signal transduction
GO:0043547 ISS positive regulation of GTPase activity
GO:0046847 ISS filopodium assembly

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000057216 arhgef4-002 protein_coding Danio_rerio 0 723
ENSDART00000133708 arhgef4-001 protein_coding Danio_rerio 0 723
ENSDART00000152031 arhgef4-003 protein_coding Danio_rerio 0 723
ENST00000326016 ARHGEF4-001 protein_coding Homo_sapiens 0 1816
ENST00000343003 SPATA13-201 protein_coding Homo_sapiens 0 398
ENST00000355771 ARHGEF4-009 protein_coding Homo_sapiens 0 1816
ENST00000382095 SPATA13-001 protein_coding Homo_sapiens 0 398
ENST00000382108 SPATA13-202 protein_coding Homo_sapiens 0 398
ENST00000382141 RP11-307N16.6-001 nonsense_mediated_decay Homo_sapiens 0 398
ENST00000392953 ARHGEF4-201 protein_coding Homo_sapiens 0 1803
ENST00000399949 SPATA13-006 protein_coding Homo_sapiens 0 398
ENST00000409126 SPATA13-011 protein_coding Homo_sapiens 0 241
ENST00000409185 FAM168B-001 protein_coding Homo_sapiens 4e-28 132
ENST00000409303 ARHGEF4-005 protein_coding Homo_sapiens 0 1219
ENST00000424834 SPATA13-008 protein_coding Homo_sapiens 0 398
ENST00000434675 SPATA13-010 protein_coding Homo_sapiens 0 241
ENST00000439368 ARHGEF4-010 processed_transcript Homo_sapiens 0 845
ENST00000490728 ARHGEF4-006 retained_intron Homo_sapiens 0 889
ENST00000496764 ARHGEF4-007 processed_transcript Homo_sapiens 0 424
ENST00000525092 ARHGEF4-014 retained_intron Homo_sapiens 0 353
ENST00000525839 ARHGEF4-002 protein_coding Homo_sapiens 0 1685
ENST00000527365 ARHGEF4-013 retained_intron Homo_sapiens 0 564
ENST00000528247 ARHGEF4-011 processed_transcript Homo_sapiens 0 566
ENST00000532720 ARHGEF4-012 protein_coding Homo_sapiens 0 1027
ENST00000611048 ARHGEF4-203 protein_coding Homo_sapiens 0 1219

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