C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: activin A receptor, type II-like 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000000542 Acvrl1-001 ENSMUSG00000000530 10090 + 15:101128522-101145336 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000000542
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000000542 3.129±0.23 3.167±0.61 2.916±0.00 2.419±0.57 3.096±0.75 1.424±0.40 2.490±0.46 0.221±0.06 1.346±0.62 3.378±1.20 5.879±4.50 0.482±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006JX CIL_0006JX_0002 CGP 15:101115755-101145336
CIL_0006JY CIL_0006JY_0002 CGP 15:101128522-101213679

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IMP angiogenesis
GO:0001701 IMP in utero embryonic development
GO:0001937 IDA negative regulation of endothelial cell proliferation
GO:0001938 IDA positive regulation of endothelial cell proliferation
GO:0001946 IMP lymphangiogenesis
GO:0001974 IMP blood vessel remodeling
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004702 IEA receptor signaling protein serine/threonine kinase activity
GO:0005024 IEA transforming growth factor beta-activated receptor activity
GO:0005025 IEA transforming growth factor beta receptor activity, type I
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005887 IEA integral component of plasma membrane
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007162 IEA negative regulation of cell adhesion
GO:0007165 IEA signal transduction
GO:0007179 IDA transforming growth factor beta receptor signaling pathway
GO:0008015 IEA blood circulation
GO:0008217 IEA regulation of blood pressure
GO:0008285 IEA negative regulation of cell proliferation
GO:0009986 IEA cell surface
GO:0010596 IEA negative regulation of endothelial cell migration
GO:0010862 IEA positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0016361 IEA activin receptor activity, type I
GO:0019901 IEA protein kinase binding
GO:0030308 IEA negative regulation of cell growth
GO:0030336 IEA negative regulation of cell migration
GO:0030425 IEA dendrite
GO:0030509 IMP BMP signaling pathway
GO:0030513 IDA positive regulation of BMP signaling pathway
GO:0032924 IEA activin receptor signaling pathway
GO:0035313 IEA wound healing, spreading of epidermal cells
GO:0042118 TAS endothelial cell activation
GO:0043025 IEA neuronal cell body
GO:0043537 IEA negative regulation of blood vessel endothelial cell migration
GO:0045602 IDA negative regulation of endothelial cell differentiation
GO:0045603 IDA positive regulation of endothelial cell differentiation
GO:0045766 IGI positive regulation of angiogenesis
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046332 IEA SMAD binding
GO:0046872 IEA metal ion binding
GO:0048185 IEA activin binding
GO:0048514 IMP blood vessel morphogenesis
GO:0050431 IEA transforming growth factor beta binding
GO:0051291 IEA protein heterooligomerization
GO:0051895 IEA negative regulation of focal adhesion assembly
GO:0060836 IMP lymphatic endothelial cell differentiation
GO:0060840 IMP artery development
GO:0060841 IMP venous blood vessel development
GO:0061154 IEA endothelial tube morphogenesis
GO:0061298 IMP retina vasculature development in camera-type eye
GO:0071560 IDA cellular response to transforming growth factor beta stimulus
GO:0071773 IEA cellular response to BMP stimulus
GO:2000279 IEA negative regulation of DNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000388922 ACVRL1-001 protein_coding Homo_sapiens 0 1574
ENST00000419526 ACVRL1-003 protein_coding Homo_sapiens 0 1146
ENST00000547632 ACVRL1-007 retained_intron Homo_sapiens 0 414
ENST00000550683 ACVRL1-002 protein_coding Homo_sapiens 0 1666
ENST00000552678 ACVRL1-008 protein_coding Homo_sapiens 0 483

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