C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: G protein-coupled receptor kinase 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000398052 GRK4-001 ENSG00000125388 9606 + 4:2963728-3040747 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BreastLiverTestisENST00000398052
Transcript ID Breast Liver Testis
ENST00000398052 0.161±0.00 0.103±0.00 42.835±29.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00056M CIL_00056M_0001 CGP 4:2937933-3040747
CIL_000748 CIL_000748_0001 CGP 4:2963608-3243959

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002029 IEA desensitization of G-protein coupled receptor protein signaling pathway
GO:0002031 IEA G-protein coupled receptor internalization
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004703 IEA G-protein coupled receptor kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005829 IEA cytosol
GO:0006468 IEA protein phosphorylation
GO:0007165 IEA signal transduction
GO:0008277 TAS:IEA regulation of G-protein coupled receptor protein signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030425 IEA dendrite
GO:0031623 IDA receptor internalization
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0043025 IEA neuronal cell body
GO:0050254 IEA rhodopsin kinase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000001112 Grk4-001 protein_coding Mus_musculus 0 1389
ENSMUST00000153323 Grk4-004 processed_transcript Mus_musculus 0 590

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