C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: junction plakoglobin
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000001592 Jup-001 ENSMUSG00000001552 10090 - 11:100370619-100397749 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000001592
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000001592 24.965±15.47 35.541±4.49 34.893±7.19 14.633±7.62 29.001±15.89 109.093±8.93 49.921±17.01 54.098±18.19 11.341±7.87 155.514±10.70 15.578±5.31 37.925±13.15 121.771±97.86 4.599±0.41

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000TS CIL_0000TS_0003 CGP 11:100347327-100397763
CIL_0005NQ CIL_0005NQ_0002 CGP 11:100368958-100414836

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000902 IBA cell morphogenesis
GO:0002159 IMP desmosome assembly
GO:0003136 IBA negative regulation of heart induction by canonical Wnt signaling pathway
GO:0003181 IBA atrioventricular valve morphogenesis
GO:0003308 IBA negative regulation of Wnt signaling pathway involved in heart development
GO:0003713 IBA transcription coactivator activity
GO:0005198 IBA structural molecule activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0005882 IDA intermediate filament
GO:0005886 IEA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005913 IDA cell-cell adherens junction
GO:0005915 IBA zonula adherens
GO:0005916 IBA fascia adherens
GO:0005925 IEA focal adhesion
GO:0007016 IBA cytoskeletal anchoring at plasma membrane
GO:0007155 IDA cell adhesion
GO:0007369 IBA gastrulation
GO:0007398 IBA ectoderm development
GO:0007399 IBA nervous system development
GO:0009898 IBA cytoplasmic side of plasma membrane
GO:0014704 IEA intercalated disc
GO:0015629 IBA actin cytoskeleton
GO:0016020 IDA membrane
GO:0016323 IBA basolateral plasma membrane
GO:0016327 IEA apicolateral plasma membrane
GO:0016328 IEA lateral plasma membrane
GO:0016331 IBA morphogenesis of embryonic epithelium
GO:0016337 IMP single organismal cell-cell adhesion
GO:0016342 IBA catenin complex
GO:0016477 IEA cell migration
GO:0019901 IBA protein kinase binding
GO:0019903 IEA protein phosphatase binding
GO:0030018 IDA Z disc
GO:0030057 IDA desmosome
GO:0030877 IBA beta-catenin destruction complex
GO:0032993 IEA protein-DNA complex
GO:0042127 IEA regulation of cell proliferation
GO:0042307 IEA positive regulation of protein import into nucleus
GO:0043588 IMP skin development
GO:0045294 IPI alpha-catenin binding
GO:0045296 IBA cadherin binding
GO:0045944 IBA positive regulation of transcription from RNA polymerase II promoter
GO:0048599 IBA oocyte development
GO:0050982 IEA detection of mechanical stimulus
GO:0051091 IEA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051291 IEA protein heterooligomerization
GO:0070062 IEA extracellular vesicular exosome
GO:0071665 IEA gamma-catenin-TCF7L2 complex
GO:0071681 IEA cellular response to indole-3-methanol
GO:0086005 IEA ventricular cardiac muscle cell action potential
GO:0086069 IEA bundle of His cell to Purkinje myocyte communication
GO:0086091 IEA regulation of heart rate by cardiac conduction
GO:0090002 IEA establishment of protein localization to plasma membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000148794 jupb-001 protein_coding Danio_rerio 0 942
ENSDART00000082080 jupb-201 protein_coding Danio_rerio 0 929
ENSDART00000003891 jupa-001 protein_coding Danio_rerio 0 848
ENSDART00000081018 jupa-201 protein_coding Danio_rerio 0 457
ENST00000310706 JUP-001 protein_coding Homo_sapiens 0 3031
ENST00000393930 JUP-004 protein_coding Homo_sapiens 0 2933
ENST00000393931 JUP-008 protein_coding Homo_sapiens 0 2953
ENST00000424457 JUP-003 protein_coding Homo_sapiens 3e-23 113
ENST00000585793 JUP-011 retained_intron Homo_sapiens 0 531
ENST00000589036 JUP-010 retained_intron Homo_sapiens 0 324
ENST00000591690 JUP-012 protein_coding Homo_sapiens 2e-23 113

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