C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: junction plakoglobin
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000310706 JUP-001 ENSG00000173801 9606 - 17:41754604-41786698 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000310706
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000310706 38.771±0.00 10.218±0.00 1.875±0.00 3.574±2.92 16.045±15.08 6.814±0.00 22.072±18.65 27.034±21.36 9.570±7.14 21.503±17.71 37.555±0.00 179.173±163.83 53.569±20.83 6.383±2.92

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000TS CIL_0000TS_0002 CGP 17:41717742-41786931
CIL_0005NQ CIL_0005NQ_0001 CGP 17:41754604-41812604

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000902 IBA cell morphogenesis
GO:0002159 IMP desmosome assembly
GO:0003136 IBA negative regulation of heart induction by canonical Wnt signaling pathway
GO:0003181 IBA atrioventricular valve morphogenesis
GO:0003308 IBA negative regulation of Wnt signaling pathway involved in heart development
GO:0003713 IDA transcription coactivator activity
GO:0005198 IBA structural molecule activity
GO:0005199 IC structural constituent of cell wall
GO:0005488 IEA binding
GO:0005515 IPI:IEA protein binding
GO:0005634 IMP nucleus
GO:0005737 IMP cytoplasm
GO:0005829 ISS cytosol
GO:0005856 ISS cytoskeleton
GO:0005886 IDA plasma membrane
GO:0005911 IDA cell-cell junction
GO:0005913 IDA cell-cell adherens junction
GO:0005915 ISS zonula adherens
GO:0005916 IBA fascia adherens
GO:0005925 IDA focal adhesion
GO:0007016 IBA cytoskeletal anchoring at plasma membrane
GO:0007369 IBA gastrulation
GO:0007398 IBA ectoderm development
GO:0007399 IBA nervous system development
GO:0009898 ISS cytoplasmic side of plasma membrane
GO:0014704 IDA intercalated disc
GO:0015629 IBA actin cytoskeleton
GO:0016323 IBA basolateral plasma membrane
GO:0016331 IBA morphogenesis of embryonic epithelium
GO:0016337 IDA single organismal cell-cell adhesion
GO:0016342 IDA catenin complex
GO:0016477 IMP cell migration
GO:0019901 IBA protein kinase binding
GO:0019903 IPI protein phosphatase binding
GO:0030018 IBA Z disc
GO:0030057 IDA desmosome
GO:0032993 IDA protein-DNA complex
GO:0034329 TAS cell junction assembly
GO:0034332 TAS adherens junction organization
GO:0042127 IDA regulation of cell proliferation
GO:0042307 IDA positive regulation of protein import into nucleus
GO:0042803 ISS protein homodimerization activity
GO:0043588 IBA skin development
GO:0045216 TAS cell-cell junction organization
GO:0045294 IPI alpha-catenin binding
GO:0045296 IPI cadherin binding
GO:0048599 IBA oocyte development
GO:0050982 IDA detection of mechanical stimulus
GO:0051091 IDA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0070062 IDA extracellular vesicular exosome
GO:0071603 ISS endothelial cell-cell adhesion
GO:0071665 IDA gamma-catenin-TCF7L2 complex
GO:0071681 IDA cellular response to indole-3-methanol
GO:0086005 IMP ventricular cardiac muscle cell action potential
GO:0086069 IMP bundle of His cell to Purkinje myocyte communication
GO:0086091 IMP regulation of heart rate by cardiac conduction
GO:0090002 IMP establishment of protein localization to plasma membrane
GO:0090263 IC positive regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000001592 Jup-001 protein_coding Mus_musculus 0 3031
ENSMUST00000107403 Jup-002 protein_coding Mus_musculus 0 2909
ENSMUST00000155746 Jup-007 processed_transcript Mus_musculus 0 660
ENSMUST00000124659 Jup-003 processed_transcript Mus_musculus 0 305
ENSMUST00000152774 Jup-006 processed_transcript Mus_musculus 0 193

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