C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase kinase kinase 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000002044 Map3k3-001 ENSMUSG00000020700 10090 + 11:106084613-106155446 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000002044
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000002044 20.486±5.50 4.974±1.79 14.961±0.40 8.535±4.42 21.613±1.87 6.133±0.00 2.694±0.00 13.619±0.93 4.947±1.72 29.676±0.66 2.009±0.00 13.137±6.84 14.652±9.35 2.292±0.56

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009B9 CIL_0009B9_0002 VISTA 11:105834084-106435839
CIL_0002QS CIL_0002QS_0002 CGP 11:106066061-106155446
CIL_0003AI CIL_0003AI_0003 CGP 11:106084613-106160860

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0000186 IEA activation of MAPKK activity
GO:0001568 IMP blood vessel development
GO:0004672 ISO protein kinase activity
GO:0004709 IEA MAP kinase kinase kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0035556 ISO intracellular signal transduction
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046777 ISO protein autophosphorylation
GO:0046872 IEA metal ion binding
GO:1900745 IDA positive regulation of p38MAPK cascade

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000091370 MAP3K2-201 protein_coding Danio_rerio 0 442
ENSDART00000151470 MAP3K2-001 protein_coding Danio_rerio 0 442
ENST00000361357 MAP3K3-001 protein_coding Homo_sapiens 0 2639
ENST00000361733 MAP3K3-004 protein_coding Homo_sapiens 0 3107
ENST00000577395 MAP3K3-005 protein_coding Homo_sapiens 0 2518
ENST00000577597 MAP3K3-006 nonsense_mediated_decay Homo_sapiens 0 2569
ENST00000577784 MAP3K3-011 processed_transcript Homo_sapiens 0 209
ENST00000577839 MAP3K3-012 retained_intron Homo_sapiens 0 388
ENST00000578622 MAP3K3-009 retained_intron Homo_sapiens 0 296
ENST00000579585 MAP3K3-007 protein_coding Homo_sapiens 0 2639
ENST00000584573 MAP3K3-002 protein_coding Homo_sapiens 0 2388

Loading