C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase kinase kinase 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000361357 MAP3K3-001 ENSG00000198909 9606 + 17:63622442-63696303 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainHeartLungOvaryTestisENST00000361357
Transcript ID Adrenal Brain Heart Lung Ovary Testis
ENST00000361357 13.529±0.00 1.413±0.00 0.881±0.00 1.979±0.00 2.898±1.06 7.443±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009B9 CIL_0009B9_0001 VISTA 17:63374232-63977730
CIL_0002QS CIL_0002QS_0001 CGP 17:63600872-63696303
CIL_0003AI CIL_0003AI_0002 CGP 17:63622415-63701172

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 TAS MAPK cascade
GO:0000186 IEA activation of MAPKK activity
GO:0001568 IEA blood vessel development
GO:0004672 IDA:IEA protein kinase activity
GO:0004709 IEA MAP kinase kinase kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005829 TAS cytosol
GO:0006468 IEA protein phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0035556 IDA intracellular signal transduction
GO:0043123 IEP positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046777 IDA protein autophosphorylation
GO:0046872 IEA metal ion binding
GO:1900745 IEA positive regulation of p38MAPK cascade

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000002044 Map3k3-001 protein_coding Mus_musculus 0 2639
ENSDART00000084932 map3k3-201 protein_coding Danio_rerio 0 514
ENSDART00000157028 map3k3-001 protein_coding Danio_rerio 0 514
ENSMUST00000045923 Limd2-001 protein_coding Mus_musculus 0 211

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