C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: lysine (K)-specific demethylase 7A
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000002305 Kdm7a-001 ENSMUSG00000042599 10090 - 6:39136623-39206789 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000002305
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000002305 4.104±1.52 3.075±0.12 2.268±0.01 2.040±0.79 3.940±1.10 3.292±0.33 1.835±0.27 1.996±0.56 2.924±1.95 4.406±1.09 2.827±0.94 6.157±1.76 0.685±0.33 2.917±0.94

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008ZU CIL_0008ZU_0002 VISTA 6:38939568-39543498
CIL_00030A CIL_00030A_0002 CGP 6:39086410-39206789
CIL_000307 CIL_000307_0002 CGP 6:39136623-39377707

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005506 ISS iron ion binding
GO:0005634 IEA nucleus
GO:0005730 IEA nucleolus
GO:0006351 IEA transcription, DNA-templated
GO:0008270 ISS zinc ion binding
GO:0016706 ISS oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0030901 ISS midbrain development
GO:0032454 IMP histone demethylase activity (H3-K9 specific)
GO:0033169 IMP histone H3-K9 demethylation
GO:0035064 ISS methylated histone binding
GO:0035574 ISS histone H4-K20 demethylation
GO:0035575 ISS histone demethylase activity (H4-K20 specific)
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0051864 ISS histone demethylase activity (H3-K36 specific)
GO:0055114 IEA oxidation-reduction process
GO:0070544 ISS histone H3-K36 demethylation
GO:0071557 IMP histone H3-K27 demethylation
GO:0071558 IMP histone demethylase activity (H3-K27 specific)

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000050379 kdm7ab-001 protein_coding Danio_rerio 0 569
ENST00000359246 PHF2-001 protein_coding Homo_sapiens 5e-33 148
ENST00000375376 PHF2-201 protein_coding Homo_sapiens 2e-33 148
ENST00000397560 KDM7A-001 protein_coding Homo_sapiens 0 5315
ENST00000472616 KDM7A-002 nonsense_mediated_decay Homo_sapiens 0 1903
ENST00000478996 KDM7A-003 retained_intron Homo_sapiens 0 621
ENST00000610682 PHF2-202 protein_coding Homo_sapiens 2e-33 148

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