C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: kit oncogene
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000005815 Kit-002 ENSMUSG00000005672 10090 + 5:75574955-75656722 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000005815
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000005815 2.701±0.97 2.081±0.22 1.770±0.16 6.903±2.89 17.323±4.26 22.478±4.39 0.366±0.00 3.519±0.72 2.054±1.40 42.210±20.67 0.085±0.01 11.035±4.52 5.552±4.34 1.928±1.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001CJ CIL_0001CJ_0002 CGP 5:75152291-75656722
CIL_0001CK CIL_0001CK_0002 CGP 5:75574916-75978458

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000187 IEA activation of MAPK activity
GO:0001541 IMP ovarian follicle development
GO:0001669 IEA acrosomal vesicle
GO:0002020 IPI protease binding
GO:0002318 IGI myeloid progenitor cell differentiation
GO:0002320 IGI lymphoid progenitor cell differentiation
GO:0002327 IMP immature B cell differentiation
GO:0002371 IMP dendritic cell cytokine production
GO:0002551 IEA mast cell chemotaxis
GO:0002573 IMP myeloid leukocyte differentiation
GO:0004714 ISS transmembrane receptor protein tyrosine kinase activity
GO:0004716 IEA receptor signaling protein tyrosine kinase activity
GO:0005020 IDA stem cell factor receptor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005615 IEA extracellular space
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005911 IDA cell-cell junction
GO:0006468 IDA protein phosphorylation
GO:0006687 IMP glycosphingolipid metabolic process
GO:0006935 TAS chemotaxis
GO:0006954 IMP inflammatory response
GO:0007281 TAS germ cell development
GO:0007283 IMP spermatogenesis
GO:0007286 IMP spermatid development
GO:0008284 IGI positive regulation of cell proliferation
GO:0008354 IEA germ cell migration
GO:0008360 IDA regulation of cell shape
GO:0008542 IEA visual learning
GO:0008584 IEA male gonad development
GO:0009314 IMP response to radiation
GO:0009897 IDA external side of plasma membrane
GO:0009898 IEA cytoplasmic side of plasma membrane
GO:0009986 IDA cell surface
GO:0010628 IMP positive regulation of gene expression
GO:0016021 IEA integral component of membrane
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0019221 IDA cytokine-mediated signaling pathway
GO:0019955 ISS cytokine binding
GO:0023014 IEA signal transduction by phosphorylation
GO:0030032 IDA lamellipodium assembly
GO:0030097 IMP hemopoiesis
GO:0030154 TAS cell differentiation
GO:0030217 IMP T cell differentiation
GO:0030218 IMP erythrocyte differentiation
GO:0030318 IMP melanocyte differentiation
GO:0030335 IEA positive regulation of cell migration
GO:0031274 IEA positive regulation of pseudopodium assembly
GO:0031532 ISS actin cytoskeleton reorganization
GO:0032762 ISS mast cell cytokine production
GO:0035019 IEA somatic stem cell maintenance
GO:0035162 IMP embryonic hemopoiesis
GO:0035234 IGI ectopic germ cell programmed cell death
GO:0035556 IDA intracellular signal transduction
GO:0035855 IMP megakaryocyte development
GO:0038093 ISS Fc receptor signaling pathway
GO:0038109 IEA Kit signaling pathway
GO:0038162 IMP erythropoietin-mediated signaling pathway
GO:0042511 IEA positive regulation of tyrosine phosphorylation of Stat1 protein
GO:0042517 IEA positive regulation of tyrosine phosphorylation of Stat3 protein
GO:0042523 IEA positive regulation of tyrosine phosphorylation of Stat5 protein
GO:0042629 IEA mast cell granule
GO:0042803 IEA protein homodimerization activity
GO:0043069 IGI negative regulation of programmed cell death
GO:0043303 ISS mast cell degranulation
GO:0043406 IGI positive regulation of MAP kinase activity
GO:0043410 IEA positive regulation of MAPK cascade
GO:0043473 IGI pigmentation
GO:0045747 IEA positive regulation of Notch signaling pathway
GO:0046427 IEA positive regulation of JAK-STAT cascade
GO:0046777 TAS protein autophosphorylation
GO:0046872 IEA metal ion binding
GO:0048066 IMP developmental pigmentation
GO:0048070 IGI regulation of developmental pigmentation
GO:0048103 IEA somatic stem cell division
GO:0048170 IEA positive regulation of long-term neuronal synaptic plasticity
GO:0048565 IMP digestive tract development
GO:0048863 IMP stem cell differentiation
GO:0050673 IEA epithelial cell proliferation
GO:0050910 IMP detection of mechanical stimulus involved in sensory perception of sound
GO:0051091 IEA positive regulation of sequence-specific DNA binding transcription factor activity
GO:0060326 ISS cell chemotaxis
GO:0060374 IMP mast cell differentiation
GO:0097067 IDA cellular response to thyroid hormone stimulus
GO:0097324 IMP melanocyte migration
GO:0097326 IDA melanocyte adhesion

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000288135 KIT-001 protein_coding Homo_sapiens 0 2702
ENST00000412167 KIT-002 protein_coding Homo_sapiens 0 2625
ENST00000512959 KIT-004 retained_intron Homo_sapiens 0 562
ENST00000514582 KIT-003 retained_intron Homo_sapiens 0 255

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