C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: serine/threonine kinase 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000018353 Stk4-001 ENSMUSG00000018209 10090 + 2:164074138-164155524 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000018353
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000018353 3.374±0.80 1.106±0.34 6.259±0.09 7.650±1.23 8.065±1.31 4.217±0.99 2.328±0.25 3.923±0.95 5.463±2.71 12.225±2.50 2.171±0.40 4.952±2.44 14.160±3.68 5.445±0.18

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002ZU CIL_0002ZU_0002 CGP 2:164025450-164071169
CIL_0003UT CIL_0003UT_0002 CGP 2:164053540-164155524
CIL_0003US CIL_0003US_0002 CGP 2:164070322-164171113

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IEA magnesium ion binding
GO:0000902 ISO cell morphogenesis
GO:0001569 IGI patterning of blood vessels
GO:0001841 IGI neural tube formation
GO:0003157 IGI endocardium development
GO:0004674 ISS protein serine/threonine kinase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006468 ISS protein phosphorylation
GO:0006915 ISS apoptotic process
GO:0007417 IGI central nervous system development
GO:0008134 IEA transcription factor binding
GO:0008285 IGI negative regulation of cell proliferation
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0030216 IGI keratinocyte differentiation
GO:0035329 IGI hippo signaling
GO:0035556 IEA intracellular signal transduction
GO:0042802 IEA identical protein binding
GO:0042803 ISO protein homodimerization activity
GO:0043065 IGI positive regulation of apoptotic process
GO:0046621 IGI negative regulation of organ growth
GO:0046777 ISO protein autophosphorylation
GO:0046983 IEA protein dimerization activity
GO:0060215 IGI primitive hemopoiesis
GO:0060706 IGI cell differentiation involved in embryonic placenta development
GO:0090090 IGI negative regulation of canonical Wnt signaling pathway
GO:0097284 IGI hepatocyte apoptotic process
GO:1902043 IGI positive regulation of extrinsic apoptotic signaling pathway via death domain receptors

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000372801 STK4-006 protein_coding Homo_sapiens 0 1821
ENST00000372806 STK4-003 protein_coding Homo_sapiens 0 2540
ENST00000474717 STK4-005 protein_coding Homo_sapiens 0 926
ENST00000480745 STK4-001 processed_transcript Homo_sapiens 0 193
ENST00000487587 STK4-002 nonsense_mediated_decay Homo_sapiens 1.99965e-42 178
ENST00000488618 STK4-004 processed_transcript Homo_sapiens 0 217
ENST00000499879 STK4-201 protein_coding Homo_sapiens 0 1760

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