C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: IL2 inducible T cell kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000020664 Itk-001 ENSMUSG00000020395 10090 - 11:46325150-46389515 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020664
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020664 0.175±0.13 0.058±0.04 0.199±0.02 0.011±0.00 4.475±2.03 0.338±0.14 0.208±0.06 0.382±0.36 0.070±0.05 1.023±0.03 0.196±0.27 0.106±0.08 1.015±0.81 0.007±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00094M CIL_00094M_0002 VISTA 11:45901358-46503267
CIL_00023X CIL_00023X_0002 CGP 11:46325150-46407982

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001865 IGI NK T cell differentiation
GO:0004713 IEA protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005911 IDA cell-cell junction
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0032609 IGI interferon-gamma production
GO:0032633 IGI interleukin-4 production
GO:0035556 IEA intracellular signal transduction

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000422843 ITK-001 protein_coding Homo_sapiens 0 2281
ENST00000519402 ITK-002 retained_intron Homo_sapiens 0 1188
ENST00000519749 ITK-005 processed_transcript Homo_sapiens 0 582
ENST00000519759 ITK-009 retained_intron Homo_sapiens 0 470
ENST00000520173 ITK-010 retained_intron Homo_sapiens 0 377
ENST00000521769 ITK-008 protein_coding Homo_sapiens 0 536

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