C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mitogen-activated protein kinase kinase 6
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000020949 Map2k6-001 ENSMUSG00000020623 10090 + 11:110399122-110513641 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020949
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020949 2.712±1.10 0.381±0.14 3.095±0.28 4.242±1.91 1.051±0.50 1.987±0.61 1.491±0.42 3.020±0.60 1.812±1.25 1.283±0.36 7.036±1.08 1.555±0.78 4.230±2.21 0.273±0.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006H0 CIL_0006H0_0002 CGP 11:110269369-110525522
CIL_00072F CIL_00072F_0002 CGP 11:110399122-111027968

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IPI MAPK cascade
GO:0000187 IMP activation of MAPK activity
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0002931 IEA response to ischemia
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004708 IEA MAP kinase kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0005856 IEA cytoskeleton
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006468 IDA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019901 IEA protein kinase binding
GO:0022602 IEA ovulation cycle process
GO:0032308 IEA positive regulation of prostaglandin secretion
GO:0042493 IEA response to drug
GO:0043065 IEA positive regulation of apoptotic process
GO:0051770 IEA positive regulation of nitric-oxide synthase biosynthetic process
GO:0060048 IMP cardiac muscle contraction
GO:0072709 IEA cellular response to sorbitol

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000316920 MAP2K3-013 protein_coding Homo_sapiens 0 492
ENST00000342679 MAP2K3-001 protein_coding Homo_sapiens 0 492
ENST00000359094 MAP2K6-005 nonsense_mediated_decay Homo_sapiens 0 1465
ENST00000361818 MAP2K3-201 protein_coding Homo_sapiens 0 492
ENST00000395491 MAP2K3-002 nonsense_mediated_decay Homo_sapiens 0 492
ENST00000496046 MAP2K3-004 nonsense_mediated_decay Homo_sapiens 0 193
ENST00000526076 MAP2K3-016 protein_coding Homo_sapiens 0 198
ENST00000586641 MAP2K6-003 retained_intron Homo_sapiens 0 1253
ENST00000588110 MAP2K6-008 protein_coding Homo_sapiens 0 514
ENST00000589295 MAP2K6-006 protein_coding Homo_sapiens 0 588
ENST00000589647 MAP2K6-004 protein_coding Homo_sapiens 0 1561
ENST00000590474 MAP2K6-001 protein_coding Homo_sapiens 0 2346
ENST00000591445 MAP2K6-002 retained_intron Homo_sapiens 0 508
ENST00000613338 MAP2K3-202 protein_coding Homo_sapiens 0 492
ENST00000613873 MAP2K6-201 protein_coding Homo_sapiens 0 1563

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