C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: receptor tyrosine kinase-like orphan receptor 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000021918 Ror2-001 ENSMUSG00000021464 10090 - 13:53109317-53286124 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021918
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021918 6.795±6.25 2.464±0.58 3.152±0.21 1.168±0.01 1.904±0.73 6.245±1.29 0.478±0.10 1.642±0.45 0.096±0.05 1.296±0.53 0.135±0.00 4.413±1.88 1.115±0.34 0.281±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00068R CIL_00068R_0002 CGP 13:52967209-53286124
CIL_0002JG CIL_0002JG_0002 CGP 13:53109312-53377365

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001501 IMP skeletal system development
GO:0001502 IMP cartilage condensation
GO:0001756 IMP somitogenesis
GO:0004714 TAS transmembrane receptor protein tyrosine kinase activity
GO:0005109 IPI frizzled binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007223 IPI Wnt signaling pathway, calcium modulating pathway
GO:0007254 IDA JNK cascade
GO:0008285 IEA negative regulation of cell proliferation
GO:0017147 IPI Wnt-protein binding
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0030154 IMP cell differentiation
GO:0030335 IEA positive regulation of cell migration
GO:0030538 IMP embryonic genitalia morphogenesis
GO:0042472 IMP inner ear morphogenesis
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0060071 IMP Wnt signaling pathway, planar cell polarity pathway
GO:0090090 IGI negative regulation of canonical Wnt signaling pathway
GO:0090263 IDA positive regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000375708 ROR2-001 protein_coding Homo_sapiens 0 3297
ENST00000375715 ROR2-002 protein_coding Homo_sapiens 0 2704
ENST00000550066 ROR2-006 processed_transcript Homo_sapiens 0 3247

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