C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: ribonucleotide reductase M2 B (TP53 inducible)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000251810 RRM2B-001 ENSG00000048392 9606 - 8:102204502-102239118 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000251810
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000251810 2.257±0.00 2.979±0.00 0.756±0.00 7.312±2.11 3.021±2.04 3.023±0.20 3.113±1.47 5.094±2.83 2.454±1.24 5.057±2.04 3.669±2.62 3.169±1.00 1.879±0.91 3.106±0.92

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00000S CIL_00000S_0001 CGP 8:102204502-102412841

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001822 IEA kidney development
GO:0003014 IEA renal system process
GO:0004748 IEA ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0006264 IEA mitochondrial DNA replication
GO:0006281 IEA DNA repair
GO:0006979 IEA response to oxidative stress
GO:0009186 IEA deoxyribonucleoside diphosphate metabolic process
GO:0009200 IEA deoxyribonucleoside triphosphate metabolic process
GO:0009263 IEA deoxyribonucleotide biosynthetic process
GO:0015949 TAS nucleobase-containing small molecule interconversion
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome
GO:1902254 IEA negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000022901 Rrm2b-001 protein_coding Mus_musculus 0 1437
ENSMUST00000137636 Rrm2b-003 protein_coding Mus_musculus 0 1214
ENSMUST00000146821 Rrm2b-004 protein_coding Mus_musculus 0 523
ENSMUST00000127362 Rrm2b-002 retained_intron Mus_musculus 0 521
ENSMUST00000144498 Rrm2b-008 nonsense_mediated_decay Mus_musculus 0 401
ENSMUST00000153481 Rrm2b-005 nonsense_mediated_decay Mus_musculus 0 401
ENSMUST00000145175 Rrm2b-007 protein_coding Mus_musculus 0 350
ENSMUST00000145155 Rrm2b-006 protein_coding Mus_musculus 0 292

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