C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Mdm2, transformed 3T3 cell double minute p53 binding protein
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000022998 Mtbp-001 ENSMUSG00000022369 10090 + 15:55557408-55626423 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungOvaryPlacentaTestisENSMUST00000022998
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000022998 0.643±0.01 0.435±0.14 1.941±0.25 3.217±0.94 0.828±0.34 0.701±0.26 1.087±0.13 7.714±3.10 1.395±0.00 1.923±1.26 3.518±1.75 4.449±1.33

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00009J CIL_00009J_0003 CGP 15:55307750-55557748
CIL_00008U CIL_00008U_0003 CGP 15:55534094-55626423
CIL_0002GD CIL_0002GD_0003 CGP 15:55557408-55906949

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000776 IDA kinetochore
GO:0000785 IEA chromatin
GO:0005515 IPI protein binding
GO:0007050 IEA cell cycle arrest
GO:0007089 IDA traversing start control point of mitotic cell cycle
GO:0008285 IDA negative regulation of cell proliferation
GO:0034501 IEA protein localization to kinetochore
GO:0045839 IDA negative regulation of mitosis
GO:0071174 IEA mitotic spindle checkpoint

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000305949 MTBP-001 protein_coding Homo_sapiens 0 1982
ENST00000456899 MTBP-005 retained_intron Homo_sapiens 0 219
ENST00000522308 MTBP-002 retained_intron Homo_sapiens 0 377
ENST00000523373 MTBP-003 nonsense_mediated_decay Homo_sapiens 0 917

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