C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: structural maintenance of chromosomes 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000025930 Smc3-001 ENSMUSG00000024974 10090 + 19:53600398-53645833 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025930
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025930 3.449±1.30 6.567±0.62 5.655±0.65 18.442±7.04 2.846±0.91 4.022±1.20 1.848±0.51 3.266±0.49 10.146±9.10 5.276±0.45 2.689±0.53 10.986±14.79 43.332±38.60 21.459±29.36

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008Q9 CIL_0008Q9_0002 VISTA 19:53415569-54017446
CIL_0006FC CIL_0006FC_0002 CGP 19:53600398-53867080

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000775 IEA chromosome, centromeric region
GO:0000785 ISS chromatin
GO:0000800 IDA lateral element
GO:0000922 ISS spindle pole
GO:0003682 IDA chromatin binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 ISS cytoplasm
GO:0006275 ISS regulation of DNA replication
GO:0006281 IEA DNA repair
GO:0007052 ISS mitotic spindle organization
GO:0007064 IEA mitotic sister chromatid cohesion
GO:0007126 ISS meiotic nuclear division
GO:0007165 ISS signal transduction
GO:0008280 IEA cohesin core heterodimer
GO:0016363 ISS nuclear matrix
GO:0019827 IMP stem cell maintenance
GO:0030893 ISS meiotic cohesin complex
GO:0032876 IEA negative regulation of DNA endoreduplication
GO:0034991 IDA nuclear meiotic cohesin complex
GO:0036033 IDA mediator complex binding
GO:0045502 ISS dynein binding
GO:0046982 IEA protein heterodimerization activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000361804 SMC3-001 protein_coding Homo_sapiens 0 5138
ENST00000424783 AC019097.7-001 processed_pseudogene Homo_sapiens 0 959
ENST00000462899 SMC3-002 processed_transcript Homo_sapiens 0 826

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