C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: macrophage scavenger receptor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000026021 Msr1-201 ENSMUSG00000025044 10090 - 8:39581700-39642678 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainColonHeartKidneyLiverMuscleOvaryPlacentaTestisENSMUST00000026021
Transcript ID Adipose Adrenal Bladder Brain Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENSMUST00000026021 0.408±0.13 0.217±0.00 0.932±0.07 0.103±0.00 0.306±0.00 0.281±0.04 0.123±0.00 1.807±0.82 0.137±0.04 0.815±0.46 0.316±0.33 3.178±0.71

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000456 CIL_000456_0002 CGP 8:39005867-39642678
CIL_0001VY CIL_0001VY_0002 CGP 8:39581700-40308331

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005044 IEA scavenger receptor activity
GO:0005515 IEA protein binding
GO:0005581 IEA collagen trimer
GO:0005829 IEA cytosol
GO:0005886 TAS plasma membrane
GO:0006898 IEA receptor-mediated endocytosis
GO:0010744 IGI positive regulation of macrophage derived foam cell differentiation
GO:0010886 IMP positive regulation of cholesterol storage
GO:0016021 IEA integral component of membrane
GO:0030169 IMP low-density lipoprotein particle binding
GO:0030301 IMP cholesterol transport
GO:0031410 IEA cytoplasmic vesicle
GO:0034362 IEA low-density lipoprotein particle
GO:0034381 IMP plasma lipoprotein particle clearance
GO:0042953 IMP lipoprotein transport
GO:0071407 IEA cellular response to organic cyclic compound

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000262101 MSR1-001 protein_coding Homo_sapiens 0 889
ENST00000350896 MSR1-201 protein_coding Homo_sapiens 8e-39 167
ENST00000355282 MSR1-002 protein_coding Homo_sapiens 4e-32 143
ENST00000445506 MSR1-004 protein_coding Homo_sapiens 0 865

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