C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: neuronal guanine nucleotide exchange factor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000027477 Ngef-002 ENSMUSG00000026259 10090 - 1:87476834-87510362 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastHeartLiverLungOvaryPlacentaTestisENSMUST00000027477
Transcript ID Adipose Adrenal Bladder Brain Breast Heart Liver Lung Ovary Placenta Testis
ENSMUST00000027477 0.668±0.52 0.127±0.06 1.992±0.26 44.642±58.08 0.436±0.17 0.183±0.04 0.568±0.00 1.779±0.26 3.456±1.13 0.457±0.35 0.345±0.17

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003HR CIL_0003HR_0002 CGP 1:87470271-87573870
CIL_0003HS CIL_0003HS_0002 CGP 1:87476834-87597845

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0009987 IDA cellular process
GO:0016020 IEA membrane
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0042995 IEA cell projection
GO:0043087 IDA regulation of GTPase activity
GO:0046875 IPI ephrin receptor binding
GO:0048013 IDA ephrin receptor signaling pathway
GO:0061002 IDA negative regulation of dendritic spine morphogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000264051 NGEF-001 protein_coding Homo_sapiens 0 2013
ENST00000373552 NGEF-003 protein_coding Homo_sapiens 0 2233
ENST00000409079 NGEF-002 protein_coding Homo_sapiens 0 841
ENST00000424488 NGEF-008 protein_coding Homo_sapiens 0 669
ENST00000461944 NGEF-007 retained_intron Homo_sapiens 0 209
ENST00000489127 NGEF-009 retained_intron Homo_sapiens 0 556

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