C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: kynureninase (L-kynurenine hydrolase)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000028223 Kynu-001 ENSMUSG00000026866 10090 + 2:43555329-43682715 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028223
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028223 0.059±0.05 0.073±0.02 0.050±0.03 0.036±0.02 0.979±0.35 0.255±0.21 0.081±0.04 5.504±2.56 23.625±23.12 0.518±0.13 0.095±0.00 0.095±0.05 1.075±0.90 0.015±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003NW CIL_0003NW_0002 CGP 2:40595248-43682715
CIL_0008RY CIL_0008RY_0002 VISTA 2:43481987-44083031
CIL_0006M7 CIL_0006M7_0002 CGP 2:43555329-44395953

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005739 IDA mitochondrion
GO:0005829 IEA cytosol
GO:0019441 IEA tryptophan catabolic process to kynurenine
GO:0019442 IEA tryptophan catabolic process to acetyl-CoA
GO:0019805 IEA quinolinate biosynthetic process
GO:0030170 IEA pyridoxal phosphate binding
GO:0030429 IEA kynureninase activity
GO:0034341 IEA response to interferon-gamma
GO:0034354 IEA 'de novo' NAD biosynthetic process from tryptophan
GO:0034516 IEA response to vitamin B6
GO:0042803 IEA protein homodimerization activity
GO:0043420 IEA anthranilate metabolic process
GO:0097053 IEA L-kynurenine catabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000264170 KYNU-001 protein_coding Homo_sapiens 0 1375
ENST00000375773 KYNU-003 protein_coding Homo_sapiens 0 976
ENST00000409512 KYNU-002 protein_coding Homo_sapiens 0 1365
ENST00000460143 KYNU-006 retained_intron Homo_sapiens 0 407
ENST00000612147 KYNU-008 protein_coding Homo_sapiens 0 560
ENST00000613664 KYNU-009 protein_coding Homo_sapiens 0 508
ENST00000621320 KYNU-007 protein_coding Homo_sapiens 0 765

Loading