C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: kynureninase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000264170 KYNU-001 ENSG00000115919 9606 + 2:142877498-143055832 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000264170
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000264170 0.239±0.00 0.402±0.00 0.209±0.00 0.118±0.11 0.187±0.01 0.079±0.05 0.097±0.06 0.684±0.44 0.434±0.00 0.297±0.17 0.047±0.00 0.050±0.03 0.081±0.03 0.282±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003NW CIL_0003NW_0001 CGP 2:140231423-143055832
CIL_0008RY CIL_0008RY_0001 VISTA 2:142856840-143457904
CIL_0006M7 CIL_0006M7_0001 CGP 2:142877498-143768352

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005737 IEA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005829 IDA cytosol
GO:0006569 IMP:IEA tryptophan catabolic process
GO:0008152 IEA metabolic process
GO:0009435 IEA NAD biosynthetic process
GO:0019441 IEA tryptophan catabolic process to kynurenine
GO:0019442 IEA tryptophan catabolic process to acetyl-CoA
GO:0019805 IDA quinolinate biosynthetic process
GO:0030170 IEA pyridoxal phosphate binding
GO:0030429 IDA:IEA kynureninase activity
GO:0034341 IDA response to interferon-gamma
GO:0034354 IEA 'de novo' NAD biosynthetic process from tryptophan
GO:0034516 IMP response to vitamin B6
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042803 IDA protein homodimerization activity
GO:0043420 IDA anthranilate metabolic process
GO:0044281 TAS small molecule metabolic process
GO:0097053 IEA L-kynurenine catabolic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000028223 Kynu-001 protein_coding Mus_musculus 0 1375
ENSMUST00000112826 Kynu-002 protein_coding Mus_musculus 0 1236
ENSMUST00000050511 Kynu-003 protein_coding Mus_musculus 0 974
ENSMUST00000148855 Kynu-006 processed_transcript Mus_musculus 0 364

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