C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: integrin alpha V
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000028499 Itgav-001 ENSMUSG00000027087 10090 + 2:83724397-83806916 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028499
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028499 6.543±3.04 5.017±0.90 12.992±0.09 2.370±0.29 5.011±0.70 4.209±0.40 2.259±0.98 12.630±0.77 2.116±0.55 6.842±0.76 1.264±0.53 11.746±2.59 12.825±5.32 0.618±0.28

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002DB CIL_0002DB_0002 CGP 2:83644435-83806916
CIL_0000Q6 CIL_0000Q6_0002 CGP 2:83724397-83883486

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001568 IMP blood vessel development
GO:0001846 IDA opsonin binding
GO:0001968 IEA fibronectin binding
GO:0002020 IEA protease binding
GO:0005080 IDA protein kinase C binding
GO:0005245 IEA voltage-gated calcium channel activity
GO:0005515 IEA protein binding
GO:0005886 IDA plasma membrane
GO:0005925 IEA focal adhesion
GO:0006954 TAS inflammatory response
GO:0007155 ISS cell adhesion
GO:0007160 TAS cell-matrix adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008284 ISS positive regulation of cell proliferation
GO:0008305 ISS integrin complex
GO:0009566 NAS fertilization
GO:0009897 IDA external side of plasma membrane
GO:0009986 ISS cell surface
GO:0010745 ISS negative regulation of macrophage derived foam cell differentiation
GO:0010888 ISS negative regulation of lipid storage
GO:0016020 IDA membrane
GO:0016049 IEA cell growth
GO:0016477 IEA cell migration
GO:0030335 IMP positive regulation of cell migration
GO:0031258 IEA lamellipodium membrane
GO:0031527 IEA filopodium membrane
GO:0031528 IEA microvillus membrane
GO:0031589 IEA cell-substrate adhesion
GO:0031994 ISS insulin-like growth factor I binding
GO:0032369 ISS negative regulation of lipid transport
GO:0032490 TAS detection of molecule of bacterial origin
GO:0032587 IEA ruffle membrane
GO:0033690 IMP positive regulation of osteoblast proliferation
GO:0034113 IEA heterotypic cell-cell adhesion
GO:0034446 IEA substrate adhesion-dependent cell spreading
GO:0034683 TAS integrin alphav-beta3 complex
GO:0034684 IEA integrin alphav-beta5 complex
GO:0034686 IEA integrin alphav-beta8 complex
GO:0035262 NAS gonad morphogenesis
GO:0035867 IEA alphav-beta3 integrin-IGF-1-IGF1R complex
GO:0035987 IEA endodermal cell differentiation
GO:0038027 IEA apolipoprotein A-I-mediated signaling pathway
GO:0042110 TAS T cell activation
GO:0043277 IMP apoptotic cell clearance
GO:0043542 TAS endothelial cell migration
GO:0045124 TAS regulation of bone resorption
GO:0045715 ISS negative regulation of low-density lipoprotein particle receptor biosynthetic process
GO:0045785 ISS positive regulation of cell adhesion
GO:0046872 IEA metal ion binding
GO:0046982 TAS protein heterodimerization activity
GO:0048041 NAS focal adhesion assembly
GO:0050431 ISS transforming growth factor beta binding
GO:0050748 ISS negative regulation of lipoprotein metabolic process
GO:0050764 ISS regulation of phagocytosis
GO:0050840 IEA extracellular matrix binding
GO:0050919 IEA negative chemotaxis
GO:0051209 TAS release of sequestered calcium ion into cytosol
GO:0060707 TAS trophoblast giant cell differentiation
GO:0070062 IEA extracellular vesicular exosome
GO:0070371 IDA ERK1 and ERK2 cascade
GO:0070588 IEA calcium ion transmembrane transport
GO:0071731 TAS response to nitric oxide
GO:0097192 IDA extrinsic apoptotic signaling pathway in absence of ligand
GO:1990430 IEA extracellular matrix protein binding
GO:2000425 IDA regulation of apoptotic cell clearance
GO:2000536 ISS negative regulation of entry of bacterium into host cell
GO:2001237 IEA negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000044314 itgav-001 protein_coding Danio_rerio 0.000000000008 79
ENST00000261023 ITGAV-001 protein_coding Homo_sapiens 0 3611
ENST00000374907 ITGAV-003 protein_coding Homo_sapiens 0 2880
ENST00000433736 ITGAV-004 protein_coding Homo_sapiens 0 3417
ENST00000460641 ITGAV-006 retained_intron Homo_sapiens 0 449
ENST00000496477 ITGAV-005 retained_intron Homo_sapiens 0 363
ENST00000496854 ITGAV-007 retained_intron Homo_sapiens 0 217

Loading