C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: leukocyte tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000028759 Ltk-001 ENSMUSG00000027297 10090 - 2:119751326-119760431 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalColonHeartLiverLungOvaryENSMUST00000028759
Transcript ID Adrenal Colon Heart Liver Lung Ovary
ENSMUST00000028759 0.351±0.04 0.446±0.09 0.052±0.00 0.047±0.00 0.194±0.00 0.099±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002WJ CIL_0002WJ_0003 CGP 2:119742337-119760431
CIL_0005IS CIL_0005IS_0003 CGP 2:119751320-119787537

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 ISS protein kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005783 IEA endoplasmic reticulum
GO:0005886 IEA plasma membrane
GO:0006468 ISS protein phosphorylation
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0008283 ISS cell proliferation
GO:0010666 IEA positive regulation of cardiac muscle cell apoptotic process
GO:0010976 IEA positive regulation of neuron projection development
GO:0014065 ISS phosphatidylinositol 3-kinase signaling
GO:0016020 ISS membrane
GO:0016021 IEA integral component of membrane
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0043066 ISS negative regulation of apoptotic process
GO:0071300 IEA cellular response to retinoic acid

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000263800 LTK-001 protein_coding Homo_sapiens 0 2254
ENST00000355166 LTK-002 protein_coding Homo_sapiens 0 1554
ENST00000453182 LTK-004 protein_coding Homo_sapiens 0 979
ENST00000561619 LTK-005 protein_coding Homo_sapiens 0 1256
ENST00000563518 LTK-003 retained_intron Homo_sapiens 0 931

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