C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: leukocyte receptor tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000263800 LTK-001 ENSG00000062524 9606 - 15:41503642-41513806 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000263800
Transcript ID Adrenal Bladder Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000263800 0.047±0.00 0.026±0.00 0.219±0.16 0.088±0.00 0.935±0.00 1.352±0.00 8.999±0.00 1.564±1.30 3.601±1.65 0.314±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002WJ CIL_0002WJ_0002 CGP 15:41493393-41513887
CIL_0005IS CIL_0005IS_0002 CGP 15:41503638-41544269

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IDA:IEA protein kinase activity
GO:0004713 TAS:IEA protein tyrosine kinase activity
GO:0004714 IEA transmembrane receptor protein tyrosine kinase activity
GO:0005524 IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006468 IDA:IEA protein phosphorylation
GO:0007165 TAS signal transduction
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0008283 IDA cell proliferation
GO:0010666 IDA positive regulation of cardiac muscle cell apoptotic process
GO:0010976 IMP positive regulation of neuron projection development
GO:0014065 IMP phosphatidylinositol 3-kinase signaling
GO:0016020 IDA membrane
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0043066 IMP negative regulation of apoptotic process
GO:0071300 IMP cellular response to retinoic acid

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000028759 Ltk-001 protein_coding Mus_musculus 0 2254
ENSMUST00000182203 Ltk-201 protein_coding Mus_musculus 0 1554
ENSMUST00000082130 Ltk-002 protein_coding Mus_musculus 0 1554
ENSMUST00000140224 Ltk-003 protein_coding Mus_musculus 0 1554
ENSMUST00000127470 Ltk-004 retained_intron Mus_musculus 0 902
ENSMUST00000134295 Ltk-005 retained_intron Mus_musculus 0 339

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