C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Rho guanine nucleotide exchange factor (GEF) 16
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000030898 Arhgef16-001 ENSMUSG00000029032 10090 - 4:154278486-154300054 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030898
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030898 1.656±0.37 0.161±0.07 3.081±0.89 0.263±0.10 2.353±0.75 31.541±6.35 0.251±0.01 19.519±2.29 1.123±0.37 4.482±0.81 0.061±0.01 1.488±0.53 23.877±15.28 0.166±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099V CIL_00099V_0002 VISTA 4:154093365-154697126
CIL_0007TB CIL_0007TB_0002 VISTA 4:154156294-154757167

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005089 ISS Rho guanyl-nucleotide exchange factor activity
GO:0005737 IEA cytoplasm
GO:0017048 IEA Rho GTPase binding
GO:0030165 IEA PDZ domain binding
GO:0030971 IEA receptor tyrosine kinase binding
GO:0032863 ISS activation of Rac GTPase activity
GO:0032864 IEA activation of Cdc42 GTPase activity
GO:0060326 ISS cell chemotaxis
GO:0090004 ISS positive regulation of establishment of protein localization to plasma membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000378371 ARHGEF16-003 protein_coding Homo_sapiens 0 1382
ENST00000378373 ARHGEF16-002 protein_coding Homo_sapiens 0 1413
ENST00000378378 ARHGEF16-001 protein_coding Homo_sapiens 0 1707
ENST00000418137 ARHGEF16-007 protein_coding Homo_sapiens 0 411
ENST00000445297 ARHGEF16-005 protein_coding Homo_sapiens 0 488
ENST00000464620 ARHGEF16-006 retained_intron Homo_sapiens 0 287
ENST00000485984 ARHGEF16-004 retained_intron Homo_sapiens 0 582

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