C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Rho guanine nucleotide exchange factor (GEF) 16
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029032 Arhgef16 10090 - 4:154278486-154301676 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030898 Arhgef16-001 154278486-154300054 protein_coding
  ENSMUST00000129189 Arhgef16-005 154282018-154287085 processed_transcript
  ENSMUST00000143141 Arhgef16-004 154278486-154282499 retained_intron
  ENSMUST00000144145 Arhgef16-003 154278486-154299892 retained_intron
  ENSMUST00000152947 Arhgef16-006 154291015-154301676 protein_coding
  ENSMUST00000154895 Arhgef16-002 154287037-154299892 protein_coding
  ENSMUST00000169623 Arhgef16-201 154278754-154301663 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030898ENSMUST00000129189ENSMUST00000143141ENSMUST00000144145ENSMUST00000152947ENSMUST00000154895ENSMUST00000169623
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030898 1.656±0.37 0.161±0.07 3.081±0.89 0.263±0.10 2.353±0.75 31.541±6.35 0.251±0.01 19.519±2.29 1.123±0.37 4.482±0.81 0.061±0.01 1.488±0.53 23.877±15.28 0.166±0.00
ENSMUST00000129189 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.141±0.05 1.534±0.00 N/A N/A
ENSMUST00000143141 N/A 0.074±0.00 N/A 0.075±0.00 N/A N/A N/A N/A N/A 1.418±0.00 N/A N/A N/A N/A
ENSMUST00000144145 0.063±0.00 0.020±0.00 0.962±0.00 0.060±0.00 N/A 5.477±0.10 0.032±0.01 3.095±0.17 0.311±0.15 1.064±0.11 0.033±0.00 0.368±0.19 5.393±2.34 0.059±0.00
ENSMUST00000152947 N/A 0.146±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.067±0.00 N/A N/A N/A
ENSMUST00000154895 N/A N/A N/A N/A N/A N/A 0.280±0.00 N/A 1.303±0.00 N/A 0.099±0.00 N/A N/A N/A
ENSMUST00000169623 0.175±0.03 0.020±0.00 1.617±0.00 0.105±0.00 0.770±0.00 N/A 0.058±0.00 N/A 0.603±0.17 N/A 0.046±0.00 1.299±0.36 14.875±12.96 0.205±0.14

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00099V CIL_00099V_0002 VISTA 4:154093365-154697126
CIL_0007TB CIL_0007TB_0002 VISTA 4:154156294-154757167

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005089 ISS Rho guanyl-nucleotide exchange factor activity
GO:0005737 IEA cytoplasm
GO:0017048 IEA Rho GTPase binding
GO:0030165 IEA PDZ domain binding
GO:0030971 IEA receptor tyrosine kinase binding
GO:0032863 ISS activation of Rac GTPase activity
GO:0032864 IEA activation of Cdc42 GTPase activity
GO:0060326 ISS cell chemotaxis
GO:0090004 ISS positive regulation of establishment of protein localization to plasma membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077114 arhgef16 Rho guanine nucleotide exchange factor (GEF) 16 protein_coding Danio_rerio
ENSG00000130762 ARHGEF16 Rho guanine nucleotide exchange factor (GEF) 16 protein_coding Homo_sapiens

Loading