C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: inositol 1,4,5-trisphosphate receptor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000032192 Itpr1-201 ENSMUSG00000030102 10090 + 6:108213118-108551109 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032192
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032192 4.702±2.00 4.502±0.87 15.239±0.00 23.731±23.45 4.467±0.81 3.395±0.70 3.176±0.99 12.755±0.00 2.190±0.81 7.746±2.85 1.586±0.19 9.635±3.12 1.183±0.88 1.850±0.27

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004TR CIL_0004TR_0002 CGP 6:108107028-108551109
CIL_00050D CIL_00050D_0002 CGP 6:108213118-108666925

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IDA response to hypoxia
GO:0005218 IDA intracellular ligand-gated calcium channel activity
GO:0005220 TAS inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0005515 IPI protein binding
GO:0005635 IDA nuclear envelope
GO:0005637 IDA nuclear inner membrane
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005783 TAS endoplasmic reticulum
GO:0005789 IDA endoplasmic reticulum membrane
GO:0005955 IDA calcineurin complex
GO:0006816 IDA calcium ion transport
GO:0009791 IMP post-embryonic development
GO:0014069 IDA postsynaptic density
GO:0016021 IEA integral component of membrane
GO:0016529 IDA sarcoplasmic reticulum
GO:0019855 IEA calcium channel inhibitor activity
GO:0031088 IEA platelet dense granule membrane
GO:0031094 IEA platelet dense tubular network
GO:0032469 IGI endoplasmic reticulum calcium ion homeostasis
GO:0035091 IDA phosphatidylinositol binding
GO:0043234 IPI protein complex
GO:0048016 IEA inositol phosphate-mediated signaling
GO:0050849 IEA negative regulation of calcium-mediated signaling
GO:0050882 IMP voluntary musculoskeletal movement
GO:0051209 IMP release of sequestered calcium ion into cytosol
GO:0070059 IMP intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070588 IEA calcium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000031993 ITPR1 (2 of 2)-201 protein_coding Danio_rerio 0 3277
ENST00000302640 ITPR1-201 protein_coding Homo_sapiens 0 9971
ENST00000354582 ITPR1-202 protein_coding Homo_sapiens 0 11680
ENST00000357086 ITPR1-001 protein_coding Homo_sapiens 0 6974
ENST00000443694 ITPR1-004 protein_coding Homo_sapiens 0 9971
ENST00000456211 ITPR1-002 protein_coding Homo_sapiens 0 5260
ENST00000463980 ITPR1-011 processed_transcript Homo_sapiens 0 2422
ENST00000467056 ITPR1-003 retained_intron Homo_sapiens 0 1526
ENST00000467545 ITPR1-018 retained_intron Homo_sapiens 0 656
ENST00000472205 ITPR1-019 retained_intron Homo_sapiens 0 710
ENST00000477577 ITPR1-005 processed_transcript Homo_sapiens 0 1491
ENST00000478515 ITPR1-020 retained_intron Homo_sapiens 0 641
ENST00000479831 ITPR1-015 retained_intron Homo_sapiens 0 462
ENST00000481415 ITPR1-016 retained_intron Homo_sapiens 0 324
ENST00000487016 ITPR1-013 retained_intron Homo_sapiens 0 412
ENST00000490572 ITPR1-017 processed_transcript Homo_sapiens 0 737
ENST00000493491 ITPR1-010 processed_transcript Homo_sapiens 0 1923
ENST00000494681 ITPR1-014 retained_intron Homo_sapiens 0 460
ENST00000544951 ITPR1-203 protein_coding Homo_sapiens 0 2394

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