C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: inositol 1,4,5-trisphosphate receptor, type 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000302640 ITPR1-201 ENSG00000150995 9606 + 3:4493348-4847840 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; MuscleENST00000302640
Transcript ID Muscle
ENST00000302640 0.073±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00050D CIL_00050D_0001 CGP 3:4493348-4985323

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 IDA response to hypoxia
GO:0005216 IEA ion channel activity
GO:0005218 ISS intracellular ligand-gated calcium channel activity
GO:0005220 ISS inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0005262 IEA calcium channel activity
GO:0005515 IPI protein binding
GO:0005635 IEA nuclear envelope
GO:0005637 IEA nuclear inner membrane
GO:0005730 IEA nucleolus
GO:0005737 IEA cytoplasm
GO:0005783 NAS endoplasmic reticulum
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005955 IEA calcineurin complex
GO:0006112 TAS energy reserve metabolic process
GO:0006811 IEA ion transport
GO:0006816 NAS calcium ion transport
GO:0007165 NAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007596 TAS blood coagulation
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0009791 IEA post-embryonic development
GO:0014069 IEA postsynaptic density
GO:0015085 TAS calcium ion transmembrane transporter activity
GO:0016020 IDA:IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016529 IEA sarcoplasmic reticulum
GO:0019855 IDA calcium channel inhibitor activity
GO:0030168 TAS platelet activation
GO:0031088 IDA platelet dense granule membrane
GO:0031094 IDA platelet dense tubular network
GO:0031095 TAS platelet dense tubular network membrane
GO:0032469 IEA endoplasmic reticulum calcium ion homeostasis
GO:0035091 ISS phosphatidylinositol binding
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0043234 IEA protein complex
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048016 IEA inositol phosphate-mediated signaling
GO:0050796 TAS regulation of insulin secretion
GO:0050849 IDA negative regulation of calcium-mediated signaling
GO:0050882 IEA voluntary musculoskeletal movement
GO:0051209 ISS release of sequestered calcium ion into cytosol
GO:0055085 IEA transmembrane transport
GO:0070059 ISS intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0070588 IEA calcium ion transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000032192 Itpr1-201 protein_coding Mus_musculus 0 9971

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