C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: solute carrier family 6 (neurotransmitter transporter, GABA), member 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000032454 Slc6a1-201 ENSMUSG00000030310 10090 + 6:114282635-114317522 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000032454
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000032454 0.017±0.01 0.010±0.00 0.016±0.01 55.636±15.09 0.179±0.06 0.136±0.02 0.019±0.01 0.013±0.00 0.037±0.05 0.075±0.01 0.054±0.04 0.029±0.01 0.136±0.15 0.083±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001LQ CIL_0001LQ_0002 CGP 6:114131241-114317522
CIL_00061I CIL_00061I_0002 CGP 6:114282635-114483296

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005328 IEA neurotransmitter:sodium symporter activity
GO:0005332 IEA gamma-aminobutyric acid:sodium symporter activity
GO:0005515 IEA protein binding
GO:0005886 IDA plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006836 IEA neurotransmitter transport
GO:0007612 IEA learning
GO:0009636 IEA response to toxic substance
GO:0009744 IEA response to sucrose
GO:0009986 IEA cell surface
GO:0010033 IEA response to organic substance
GO:0010243 IEA response to organonitrogen compound
GO:0010288 IEA response to lead ion
GO:0014054 IEA positive regulation of gamma-aminobutyric acid secretion
GO:0014070 IEA response to organic cyclic compound
GO:0014074 IEA response to purine-containing compound
GO:0030424 IDA axon
GO:0032229 IEA negative regulation of synaptic transmission, GABAergic
GO:0032355 IEA response to estradiol
GO:0042220 IEA response to cocaine
GO:0043005 IEA neuron projection
GO:0051260 IEA protein homooligomerization
GO:0051592 IEA response to calcium ion
GO:0051939 IEA gamma-aminobutyric acid import
GO:0055085 IEA transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000057952 slc6a1b-202 protein_coding Danio_rerio 0 1118
ENSDART00000017551 slc6a1b-201 protein_coding Danio_rerio 0 1118
ENSDART00000124613 slc6a1a-201 protein_coding Danio_rerio 0 983
ENSDART00000133701 slc6a1a-001 protein_coding Danio_rerio 0 983
ENST00000287766 SLC6A1-001 protein_coding Homo_sapiens 0 2475
ENST00000460480 SLC6A1-004 processed_transcript Homo_sapiens 0 431

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