C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Bruton agammaglobulinemia tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000033617 Btk-001 ENSMUSG00000031264 10090 - X:134542336-134583140 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033617
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033617 0.666±0.09 0.180±0.10 1.072±0.26 0.100±0.04 2.249±1.08 0.334±0.11 0.267±0.08 0.227±0.11 3.503±3.69 1.066±0.47 0.170±0.18 0.466±0.40 0.392±0.13 0.126±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000DX CIL_0000DX_0002 CGP X:134537256-134583570
CIL_0000DV CIL_0000DV_0002 CGP X:134542336-134588062

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002553 IEA histamine secretion by mast cell
GO:0004713 IDA protein tyrosine kinase activity
GO:0004715 IEA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005547 IEA phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006468 IDA protein phosphorylation
GO:0006915 IEA apoptotic process
GO:0007249 IMP I-kappaB kinase/NF-kappaB signaling
GO:0010033 IEA response to organic substance
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0031410 IDA cytoplasmic vesicle
GO:0034614 IEA cellular response to reactive oxygen species
GO:0042629 IEA mast cell granule
GO:0042802 IEA identical protein binding
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0045087 IEA innate immune response
GO:0045121 IEA membrane raft
GO:0046777 IEA protein autophosphorylation
GO:0046872 IEA metal ion binding
GO:0048469 IMP cell maturation
GO:0048471 IEA perinuclear region of cytoplasm
GO:0071226 IEA cellular response to molecule of fungal origin

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000308731 BTK-006 protein_coding Homo_sapiens 0 2937
ENST00000372880 BTK-201 protein_coding Homo_sapiens 0 1421
ENST00000464006 BTK-003 processed_transcript Homo_sapiens 0 265
ENST00000464567 BTK-004 processed_transcript Homo_sapiens 0 455
ENST00000470069 BTK-008 processed_transcript Homo_sapiens 0 383
ENST00000470329 BTK-002 retained_intron Homo_sapiens 0 405
ENST00000478995 BTK-001 retained_intron Homo_sapiens 0 370
ENST00000488970 BTK-005 processed_transcript Homo_sapiens 0 213
ENST00000618050 BTK-202 protein_coding Homo_sapiens 0 2758
ENST00000621635 BTK-203 protein_coding Homo_sapiens 0 2778

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