C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: Bruton agammaglobulinemia tyrosine kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000621635 BTK-203 ENSG00000010671 9606 - X:101349447-101390796 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; TestisENST00000621635
Transcript ID Testis
ENST00000621635 0.133±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000DX CIL_0000DX_0001 CGP X:101345661-101390796
CIL_0000DV CIL_0000DV_0001 CGP X:101349447-101396154

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002250 TAS adaptive immune response
GO:0002553 IEA histamine secretion by mast cell
GO:0002721 TAS regulation of B cell cytokine production
GO:0002755 TAS MyD88-dependent toll-like receptor signaling pathway
GO:0002902 TAS regulation of B cell apoptotic process
GO:0004672 IEA protein kinase activity
GO:0004713 TAS:IEA protein tyrosine kinase activity
GO:0004715 TAS non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 TAS:IEA ATP binding
GO:0005547 IDA phosphatidylinositol-3,4,5-trisphosphate binding
GO:0005634 TAS nucleus
GO:0005737 TAS cytoplasm
GO:0005829 IDA cytosol
GO:0005886 IDA plasma membrane
GO:0006351 IEA transcription, DNA-templated
GO:0006468 TAS:IEA protein phosphorylation
GO:0007249 IEA I-kappaB kinase/NF-kappaB signaling
GO:0007498 TAS mesoderm development
GO:0010033 IEA response to organic substance
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0019722 TAS calcium-mediated signaling
GO:0031410 IEA cytoplasmic vesicle
GO:0034134 TAS toll-like receptor 2 signaling pathway
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0034614 IEA cellular response to reactive oxygen species
GO:0035556 TAS:IEA intracellular signal transduction
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0038123 TAS toll-like receptor TLR1:TLR2 signaling pathway
GO:0038124 TAS toll-like receptor TLR6:TLR2 signaling pathway
GO:0042113 TAS B cell activation
GO:0042629 IEA mast cell granule
GO:0042802 IPI identical protein binding
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0045087 TAS innate immune response
GO:0045121 IDA membrane raft
GO:0045579 TAS positive regulation of B cell differentiation
GO:0046777 IEA protein autophosphorylation
GO:0046872 IEA metal ion binding
GO:0048469 IEA cell maturation
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050853 TAS B cell receptor signaling pathway
GO:0051092 TAS positive regulation of NF-kappaB transcription factor activity
GO:0071226 IEA cellular response to molecule of fungal origin
GO:0097190 TAS apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000033617 Btk-001 protein_coding Mus_musculus 0 2778
ENSMUST00000132664 Btk-005 retained_intron Mus_musculus 0 2167
ENSMUST00000113213 Btk-002 protein_coding Mus_musculus 0 1421
ENSMUST00000150245 Btk-004 processed_transcript Mus_musculus 0 453
ENSMUST00000128333 Btk-003 processed_transcript Mus_musculus 0 370

Loading