C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: interleukin-1 receptor-associated kinase 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000033769 Irak1-003 ENSMUSG00000031392 10090 - X:74014971-74023913 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastHeartKidneyLiverOvaryPlacentaTestisENSMUST00000033769
Transcript ID Adipose Brain Breast Heart Kidney Liver Ovary Placenta Testis
ENSMUST00000033769 9.116±0.68 5.001±0.00 7.694±0.57 5.429±0.38 5.298±1.03 3.117±0.63 17.265±8.00 5.376±3.97 0.819±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007F4 CIL_0007F4_0002 CGP X:73942792-74023918
CIL_0007GC CIL_0007GC_0003 CGP X:74013914-74135363

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001959 IEA regulation of cytokine-mediated signaling pathway
GO:0004672 IDA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005149 IPI interleukin-1 receptor binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0007250 IEA activation of NF-kappaB-inducing kinase activity
GO:0007254 IEA JNK cascade
GO:0007568 IEA aging
GO:0016020 IEA membrane
GO:0016301 IEA kinase activity
GO:0019221 IDA cytokine-mediated signaling pathway
GO:0031072 IEA heat shock protein binding
GO:0031663 IDA lipopolysaccharide-mediated signaling pathway
GO:0032088 IEA negative regulation of NF-kappaB transcription factor activity
GO:0032494 IDA response to peptidoglycan
GO:0032496 IDA response to lipopolysaccharide
GO:0034134 IDA toll-like receptor 2 signaling pathway
GO:0034142 IDA toll-like receptor 4 signaling pathway
GO:0034605 IEA cellular response to heat
GO:0042803 IEA protein homodimerization activity
GO:0043123 IEA positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0046777 IDA protein autophosphorylation
GO:0046982 IEA protein heterodimerization activity
GO:0048661 IEA positive regulation of smooth muscle cell proliferation
GO:0051092 IDA positive regulation of NF-kappaB transcription factor activity
GO:0051259 IEA protein oligomerization
GO:0070498 IDA interleukin-1-mediated signaling pathway
GO:0070555 IEA response to interleukin-1
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0071456 IEA cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000369973 IRAK1-004 nonsense_mediated_decay Homo_sapiens 0 638
ENST00000369974 IRAK1-001 protein_coding Homo_sapiens 0 1413
ENST00000369980 IRAK1-012 protein_coding Homo_sapiens 0 1712
ENST00000393687 IRAK1-002 protein_coding Homo_sapiens 0 1537
ENST00000429936 IRAK1-020 protein_coding Homo_sapiens 0 1338
ENST00000444230 IRAK1-017 protein_coding Homo_sapiens 0 636

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