C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: Rho guanine nucleotide exchange factor (GEF7)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000033908 Arhgef7-005 ENSMUSG00000031511 10090 + 8:11728105-11823061 protein_coding

Expression Patterns

No expression data.

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00080T CIL_00080T_0002 VISTA 8:11596202-12196925
CIL_0007MP CIL_0007MP_0002 UCNEbase 8:11623645-11913000
CIL_00012L CIL_00012L_0002 CGP 8:11728105-11855761

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002244 IGI hematopoietic progenitor cell differentiation
GO:0005089 IEA Rho guanyl-nucleotide exchange factor activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0007399 IEA nervous system development
GO:0019901 IPI protein kinase binding
GO:0030027 IDA lamellipodium
GO:0030032 IMP lamellipodium assembly
GO:0030054 IEA cell junction
GO:0032855 IMP positive regulation of Rac GTPase activity
GO:0035556 IEA intracellular signal transduction
GO:0043065 ISS positive regulation of apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000218789 ARHGEF7-001 protein_coding Homo_sapiens 0 2104
ENST00000317133 ARHGEF7-008 protein_coding Homo_sapiens 0 2440
ENST00000375723 ARHGEF7-005 protein_coding Homo_sapiens 0 1982
ENST00000375736 ARHGEF7-007 protein_coding Homo_sapiens 0 2106
ENST00000375739 ARHGEF7-201 protein_coding Homo_sapiens 0 1982
ENST00000375741 ARHGEF7-202 protein_coding Homo_sapiens 0 1982
ENST00000426073 ARHGEF7-004 protein_coding Homo_sapiens 0 1984
ENST00000426768 ARHGEF7-009 protein_coding Homo_sapiens 0 459
ENST00000449979 ARHGEF7-003 protein_coding Homo_sapiens 0 455
ENST00000466143 ARHGEF7-013 protein_coding Homo_sapiens 0 1748
ENST00000467053 ARHGEF7-016 protein_coding Homo_sapiens 0 453
ENST00000469877 ARHGEF7-012 nonsense_mediated_decay Homo_sapiens 0 335
ENST00000478679 ARHGEF7-011 protein_coding Homo_sapiens 0 1428
ENST00000483540 ARHGEF7-014 processed_transcript Homo_sapiens 7e-17 92
ENST00000491688 ARHGEF7-006 processed_transcript Homo_sapiens 0 387
ENST00000491775 ARHGEF7-015 protein_coding Homo_sapiens 0 246
ENST00000544132 ARHGEF7-018 protein_coding Homo_sapiens 0 348

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