C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cholinergic receptor, nicotinic, beta polypeptide 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000034854 Chrnb4-201 ENSMUSG00000035200 10090 - 9:55028156-55048544 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034854
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034854 0.105±0.09 3.183±1.11 0.109±0.01 0.422±0.26 0.692±0.15 1.631±0.44 0.094±0.03 0.265±0.15 0.010±0.00 0.104±0.03 0.031±0.02 0.049±0.02 0.069±0.05 0.281±0.19

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001KZ CIL_0001KZ_0002 CGP 9:55011343-55048544

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001508 IGI action potential
GO:0004889 IEA acetylcholine-activated cation-selective channel activity
GO:0005886 ISO plasma membrane
GO:0006939 IGI smooth muscle contraction
GO:0006940 IMP regulation of smooth muscle contraction
GO:0007165 IEA signal transduction
GO:0007626 IMP locomotory behavior
GO:0015464 IEA acetylcholine receptor activity
GO:0016021 IEA integral component of membrane
GO:0030054 IEA cell junction
GO:0035094 IGI response to nicotine
GO:0035095 IMP behavioral response to nicotine
GO:0042391 IGI regulation of membrane potential
GO:0045211 IEA postsynaptic membrane
GO:0060084 IGI synaptic transmission involved in micturition
GO:0098655 IEA cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000008870 CHRNB4-201 protein_coding Danio_rerio 0 549
ENST00000261751 CHRNB4-001 protein_coding Homo_sapiens 0 1539
ENST00000368476 CHRNB2-001 protein_coding Homo_sapiens 0 582
ENST00000412074 CHRNB4-003 protein_coding Homo_sapiens 0 364
ENST00000559849 CHRNB4-002 nonsense_mediated_decay Homo_sapiens 0 750
ENST00000560511 CHRNB4-004 processed_transcript Homo_sapiens 0 363
ENST00000566048 RP11-483E23.7-001 unprocessed_pseudogene Homo_sapiens 7e-37 156
ENST00000568969 RP11-536P16.2-001 unprocessed_pseudogene Homo_sapiens 6e-37 156

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