C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: cathepsin H
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000034915 Ctsh-001 ENSMUSG00000032359 10090 + 9:90054267-90076089 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034915
Transcript ID Adipose Adrenal Bladder Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034915 26.450±5.40 17.588±4.88 51.111±5.19 23.507±3.30 10.572±4.43 6.194±2.38 23.200±0.00 37.684±23.83 34.489±1.64 0.715±0.14 10.642±4.39 99.204±28.15 2.559±0.71

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00058A CIL_00058A_0002 CGP 9:89909908-90076089
CIL_00085Y CIL_00085Y_0002 VISTA 9:90013787-90616367

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001520 IEA outer dense fiber
GO:0001656 ISS metanephros development
GO:0001669 IEA acrosomal vesicle
GO:0001913 IGI T cell mediated cytotoxicity
GO:0002250 IEA adaptive immune response
GO:0002764 ISS immune response-regulating signaling pathway
GO:0004175 ISS endopeptidase activity
GO:0004177 ISS aminopeptidase activity
GO:0004197 IDA cysteine-type endopeptidase activity
GO:0004252 IMP serine-type endopeptidase activity
GO:0005515 IEA protein binding
GO:0005615 ISS extracellular space
GO:0005764 ISS lysosome
GO:0005829 ISS cytosol
GO:0005930 IEA axoneme
GO:0006508 ISS proteolysis
GO:0006915 IGI apoptotic process
GO:0006919 IGI activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007283 IEA spermatogenesis
GO:0008233 IEA peptidase activity
GO:0008234 ISS cysteine-type peptidase activity
GO:0008284 IMP positive regulation of cell proliferation
GO:0008656 IGI cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0010628 ISS positive regulation of gene expression
GO:0010634 IMP positive regulation of epithelial cell migration
GO:0010813 ISS neuropeptide catabolic process
GO:0010815 ISS bradykinin catabolic process
GO:0010952 IGI positive regulation of peptidase activity
GO:0016505 IGI peptidase activator activity involved in apoptotic process
GO:0030108 ISS HLA-A specific activating MHC class I receptor activity
GO:0030335 ISS positive regulation of cell migration
GO:0030984 IEA kininogen binding
GO:0031638 IMP zymogen activation
GO:0031648 IMP protein destabilization
GO:0032403 IEA protein complex binding
GO:0032526 IDA response to retinoic acid
GO:0033619 IMP membrane protein proteolysis
GO:0043066 IMP negative regulation of apoptotic process
GO:0043129 ISS surfactant homeostasis
GO:0043621 IEA protein self-association
GO:0045766 IMP positive regulation of angiogenesis
GO:0060448 IMP dichotomous subdivision of terminal units involved in lung branching
GO:0070062 IEA extracellular vesicular exosome
GO:0070324 ISS thyroid hormone binding
GO:0070371 ISS ERK1 and ERK2 cascade
GO:0097067 IEA cellular response to thyroid hormone stimulus
GO:0097208 ISS alveolar lamellar body
GO:2001235 IGI positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000220166 CTSH-001 protein_coding Homo_sapiens 0 915
ENST00000525807 CTSH-002 nonsense_mediated_decay Homo_sapiens 0 516
ENST00000527715 CTSH-005 retained_intron Homo_sapiens 0 320
ENST00000528191 CTSH-015 processed_transcript Homo_sapiens 0 276
ENST00000528741 CTSH-007 protein_coding Homo_sapiens 0 521
ENST00000529263 CTSH-019 retained_intron Homo_sapiens 0 507
ENST00000529612 CTSH-016 retained_intron Homo_sapiens 0 425
ENST00000529861 CTSH-008 nonsense_mediated_decay Homo_sapiens 0 545
ENST00000530010 CTSH-012 retained_intron Homo_sapiens 0 390
ENST00000530929 CTSH-006 retained_intron Homo_sapiens 0 348
ENST00000533777 CTSH-003 nonsense_mediated_decay Homo_sapiens 0 468
ENST00000534038 CTSH-009 processed_transcript Homo_sapiens 0 449
ENST00000534237 CTSH-017 processed_transcript Homo_sapiens 0 468
ENST00000534533 CTSH-014 processed_transcript Homo_sapiens 0 606
ENST00000615999 CTSH-201 protein_coding Homo_sapiens 0 889

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