C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: malic enzyme 1, NADP(+)-dependent, cytosolic
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000034989 Me1-001 ENSMUSG00000032418 10090 - 9:86581371-86695953 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000034989
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000034989 224.349±46.09 247.709±70.17 48.890±3.86 9.610±3.99 156.581±73.04 5.750±1.13 33.918±1.64 79.519±4.43 18.874±18.87 23.656±4.42 77.364±7.69 116.599±58.17 17.791±5.40 66.651±15.91

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000670 CIL_000670_0002 CGP 9:86571991-86695953
CIL_000625 CIL_000625_0003 CGP 9:86581371-86758443

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004470 ISS malic enzyme activity
GO:0004471 IEA malate dehydrogenase (decarboxylating) (NAD+) activity
GO:0004473 ISS malate dehydrogenase (decarboxylating) (NADP+) activity
GO:0005515 IPI protein binding
GO:0005739 IDA mitochondrion
GO:0005829 ISS cytosol
GO:0006108 ISS malate metabolic process
GO:0008948 IEA oxaloacetate decarboxylase activity
GO:0009725 ISS response to hormone
GO:0030145 ISS manganese ion binding
GO:0051262 IDA protein tetramerization
GO:0051287 IEA NAD binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000075218 me1-201 protein_coding Danio_rerio 0 379
ENSDART00000147941 me1-001 protein_coding Danio_rerio 0 375
ENSDART00000101969 me1-002 protein_coding Danio_rerio 0 375
ENSDART00000149096 me1-003 retained_intron Danio_rerio 1e-31 143
ENST00000369705 ME1-001 protein_coding Homo_sapiens 0 2028

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