C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: mutL homolog 1 (E. coli)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000035079 Mlh1-001 ENSMUSG00000032498 10090 - 9:111228254-111271608 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000035079
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000035079 2.895±1.34 2.228±0.48 4.037±0.17 4.124±2.47 2.192±0.57 1.874±0.32 1.673±0.22 2.483±0.78 6.335±3.77 1.880±0.31 1.935±0.29 3.938±1.55 6.873±2.17 1.474±0.67

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000289 IMP nuclear-transcribed mRNA poly(A) tail shortening
GO:0000712 IMP resolution of meiotic recombination intermediates
GO:0000793 IDA condensed chromosome
GO:0000794 IDA condensed nuclear chromosome
GO:0000795 IDA synaptonemal complex
GO:0001673 IDA male germ cell nucleus
GO:0002204 IGI somatic recombination of immunoglobulin genes involved in immune response
GO:0003697 IBA single-stranded DNA binding
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005694 IDA chromosome
GO:0005712 IDA chiasma
GO:0006200 IBA ATP catabolic process
GO:0006281 IMP DNA repair
GO:0006298 IMP mismatch repair
GO:0006303 IMP double-strand break repair via nonhomologous end joining
GO:0006974 IGI cellular response to DNA damage stimulus
GO:0007060 IMP male meiosis chromosome segregation
GO:0007126 TAS meiotic nuclear division
GO:0007129 IMP synapsis
GO:0007131 IMP reciprocal meiotic recombination
GO:0007140 IMP male meiosis
GO:0007283 IMP spermatogenesis
GO:0008630 IMP intrinsic apoptotic signaling pathway in response to DNA damage
GO:0016020 IEA membrane
GO:0016446 IMP somatic hypermutation of immunoglobulin genes
GO:0016447 IMP somatic recombination of immunoglobulin gene segments
GO:0016887 IBA ATPase activity
GO:0032137 IGI guanine/thymine mispair binding
GO:0032389 IDA MutLalpha complex
GO:0032407 IEA MutSalpha complex binding
GO:0043060 IMP meiotic metaphase I plate congression
GO:0043566 IDA structure-specific DNA binding
GO:0045132 IMP meiotic chromosome segregation
GO:0045190 IMP isotype switching
GO:0045950 IMP negative regulation of mitotic recombination
GO:0048477 IMP oogenesis
GO:0051257 IMP spindle midzone assembly involved in meiosis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000231790 MLH1-001 protein_coding Homo_sapiens 0 2571
ENST00000413740 MLH1-011 protein_coding Homo_sapiens 0 298
ENST00000429117 MLH1-016 protein_coding Homo_sapiens 0 538
ENST00000432299 MLH1-002 nonsense_mediated_decay Homo_sapiens 0 754
ENST00000435176 MLH1-006 protein_coding Homo_sapiens 0 2396
ENST00000441265 MLH1-020 protein_coding Homo_sapiens 0 675
ENST00000442249 MLH1-013 nonsense_mediated_decay Homo_sapiens 0 575
ENST00000454028 MLH1-018 nonsense_mediated_decay Homo_sapiens 0 682
ENST00000455445 MLH1-005 protein_coding Homo_sapiens 0 2414
ENST00000456676 MLH1-003 protein_coding Homo_sapiens 0 2026
ENST00000457004 MLH1-012 nonsense_mediated_decay Homo_sapiens 0 588
ENST00000458009 MLH1-008 nonsense_mediated_decay Homo_sapiens 0 316
ENST00000458205 MLH1-004 protein_coding Homo_sapiens 0 2313
ENST00000466900 MLH1-019 processed_transcript Homo_sapiens 0 351
ENST00000476172 MLH1-014 processed_transcript Homo_sapiens 0 261
ENST00000485889 MLH1-017 processed_transcript Homo_sapiens 0 590
ENST00000492474 MLH1-015 processed_transcript Homo_sapiens 0 595
ENST00000536378 MLH1-201 protein_coding Homo_sapiens 0 2313
ENST00000539477 MLH1-202 protein_coding Homo_sapiens 0 1860
ENST00000616768 MLH1-021 protein_coding Homo_sapiens 0 612

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